Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 3/20 | 0.42 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | RORA | P35398 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | RORB | Q92753 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4854120 | 0.94 | CNR2 (0.45) | ALDH1A1MTNR1AMTNR1BKDM4ETLR8 | |
| SCHEMBL27547723 | 0.87 | ALDH1A1 (0.58) | ALDH1A1MTNR1AMTNR1BKDM4ETLR8 | |
| SCHEMBL9416226 | 0.86 | ALDH1A1 (0.61) | ALDH1A1MTNR1AMTNR1BKDM4ETLR8 | |
| SCHEMBL28404354 | 0.86 | ALDH1A1 (0.45) | ALDH1A1MTNR1AMTNR1BKDM4EL3MBTL1 | |
| SCHEMBL11659560 | 0.85 | ALDH1A1 (0.50) | ALDH1A1MTNR1AMTNR1BKDM4ETLR8 | |
| SCHEMBL9168453 | 0.85 | HTR1D (0.50) | ALDH1A1MTNR1AMTNR1BL3MBTL1TSHR | |
| SCHEMBL11657927 | 0.85 | GRIK1 (0.54) | ALDH1A1MTNR1AMTNR1BKDM4EL3MBTL1 | |
| SCHEMBL11659369 | 0.84 | PTGS2 (0.56) | ALDH1A1MTNR1AMTNR1BKDM4ETLR8 | |
| SCHEMBL11663572 | 0.82 | ALDH1A1 (0.60) | ALDH1A1MTNR1AMTNR1BKDM4ETLR8 | |
| SCHEMBL11664571 | 0.81 | ALDH1A1 (0.58) | ALDH1A1MTNR1AMTNR1BKDM4ETLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9206124-B2 | Treatment of drug-resistant cancer with 2-aryl-2-(3-indolyl) acetohydroxamates | NEW MEXICO TECHNICAL RESEARCH FOUNDATION (US) | 2015-12-08 | — | — | US | disclosed |
| US-20150105439-A1 | TREATMENT OF DRUG-RESISTANT CANCER WITH 2-ARYL-2-(3-INDOLYL) ACETOHYDROXAMATES | NEW MEXICO TECH UNIVERSITY RESEARCH PARK CORPORATION | 2015-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150105439-A1 | TREATMENT OF DRUG-RESISTANT CANCER WITH 2-ARYL-2-(3-INDOLYL) ACETOHYDROXAMATES | AADAC, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, ABCC1 | ALDH1A1 443/4885MTNR1A 3284/4885MTNR1B 3626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.