Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15665488 | 1.00 | MGLL (0.45) | MGLLGAAMEN1KMT2ATSHR | |
| Methyl Alcohol SCHEMBL28042472 | 0.96 | MGLL (0.42) | MGLLGAAMEN1KMT2ATSHR | |
| SCHEMBL28453296 | 0.89 | MGLL (0.54) | MGLLGAAMAPK1ALDH1A1HTT | |
| SCHEMBL169531 | 0.87 | MGLL (0.37) | MGLLGAAMAPK1ALDH1A1NSD2 | |
| SCHEMBL12931124 | 0.78 | MGLL (0.77) | MGLLGAAMAPK1ALDH1A1HTT | |
| SCHEMBL1159911 | 0.76 | MGLL (0.80) | MGLLMEN1KMT2ATSHRMAPK1 | |
| SCHEMBL16120722 | 0.76 | MGLL (0.80) | MGLLMEN1KMT2ATSHRMAPK1 | |
| SCHEMBL22311911 | 0.76 | MGLL (0.80) | MGLLMEN1KMT2ATSHRMAPK1 | |
| SCHEMBL22311941 | 0.76 | MGLL (0.80) | MGLLMEN1KMT2ATSHRMAPK1 | |
| SCHEMBL31647549 | 0.76 | MGLL (0.80) | MGLLMEN1KMT2ATSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240082417-A1 | PROTEIN-POLYMER DRUG CONJUGATES | ASANA BIOSCIENCES, LLC | 2024-03-14 | — | — | US | disclosed |
| US-20230183326-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | ASANA BIOSCIENCES, LLC | 2023-06-15 | — | — | US | disclosed |
| CN-115068626-A | Protein-polymer-drug conjugates | 阿萨纳生物科技有限责任公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-105813655-B | Protein-polymer-drug conjugates | 阿萨纳生物科技有限责任公司 | 2022-03-15 | — | — | CN | disclosed |
| CN-105979970-B | Protein-polymer-drug conjugate | 梅尔莎纳医疗公司 | 2019-09-10 | — | — | CN | disclosed |
| EP-3054992-B1 | PROTEIN-POLYMER-DRUG CONJUGATES | ASANA BIOSCIENCES LLC (US) | 2019-08-14 | — | — | EP | disclosed |
| US-20190241649-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | MERSANA THERAPEUTICS, INC. | 2019-08-08 | — | — | US | disclosed |
| US-10316080-B2 | Protein-polymer-drug conjugates | ASANA BIOSCIENCES, LLC (US) | 2019-06-11 | — | — | US | disclosed |
| EP-3054991-B1 | PROTEIN-POLYMER-DRUG CONJUGATES | MERSANA THERAPEUTICS INC (US) | 2019-04-03 | — | — | EP | disclosed |
| US-20180140716-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | MERSANA THERAPEUTICS, INC. | 2018-05-24 | — | — | US | disclosed |
| US-9849191-B2 | Protein-polymer-drug conjugates | MERSANA THERAPEUTICS, INC. (US) | 2017-12-26 | — | — | US | disclosed |
| CN-105979970-A | Protein-polymer-drug conjugates | 梅尔莎纳医疗公司 | 2016-09-28 | — | — | CN | disclosed |
| EP-3054992-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | Asana BioSciences, LLC (US) | 2016-08-17 | — | — | EP | disclosed |
| EP-3054991-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | Mersana Therapeutics, Inc. (US) | 2016-08-17 | — | — | EP | disclosed |
| CN-105813655-A | Protein-polymer-drug conjugates | 阿萨纳生物科技有限责任公司 | 2016-07-27 | — | — | CN | disclosed |
| US-20150125474-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | MERSANA THERAPEUTICS, INC. | 2015-05-07 | — | — | US | disclosed |
| WO-2015054669-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | ASANA BIOSCIENCES, LLC (US) | 2015-04-16 | — | — | WO | disclosed |
| WO-2015054659-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | MERSANA THERAPEUTICS, INC. (US) | 2015-04-16 | — | — | WO | disclosed |
| US-20150104407-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | MERSANA THERAPEUTICS, INC. | 2015-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150104407-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | PBRM1, STAMBP, TSPO | MGLL 4231/4885GAA 2569/4885MEN1 2537/4885 |
| US-20190241649-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | PBRM1, STAMBP, TSPO | MGLL 4231/4885GAA 2569/4885MEN1 2537/4885 |
| US-10316080-B2 | Protein-polymer-drug conjugates | PBRM1, STAMBP, TSPO | MGLL 4231/4885GAA 2569/4885MEN1 2537/4885 |
| US-20230183326-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | PBRM1, STAMBP, TSPO | MGLL 4231/4885GAA 2569/4885MEN1 2537/4885 |
| US-20180140716-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | PBRM1, STAMBP, TSPO | MGLL 4231/4885GAA 2569/4885MEN1 2537/4885 |
| US-20150125474-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | PBRM1, STAMBP, TSPO | MGLL 4231/4885GAA 2569/4885MEN1 2537/4885 |
| US-20240082417-A1 | PROTEIN-POLYMER DRUG CONJUGATES | PBRM1, STAMBP, TSPO | MGLL 4167/4885GAA 2625/4885MEN1 2540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.