Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1583729 | 0.88 | PTGDR2 (0.39) | PTGDR2LMNAHPGDTSHRHRH3 | |
| SCHEMBL1663380 | 0.85 | PTGDR2 (0.44) | PTGDR2LMNAHPGDTSHRHRH3 | |
| SCHEMBL1583535 | 0.84 | HRH3 (0.49) | HRH3 | |
| SCHEMBL1662800 | 0.83 | PTGDR2 (0.44) | PTGDR2LMNATSHRALDH1A1POLB | |
| SCHEMBL1663275 | 0.83 | GALR2 (0.43) | LMNAHPGDTSHRALDH1A1ABHD6 | |
| SCHEMBL1583807 | 0.82 | HRH3 (0.42) | PTGDR2LMNAHRH3 | |
| SCHEMBL1583384 | 0.81 | KDM4E (0.48) | LMNAHPGDHRH3ALDH1A1ROCK2 | |
| SCHEMBL1662724 | 0.80 | CPS1 (0.44) | PTGDR2LMNAHPGDTSHRALDH1A1 | |
| SCHEMBL1584282 | 0.79 | SCN9A (0.40) | HPGDHRH3ROCK2SMN1; SMN2 | |
| SCHEMBL1583489 | 0.78 | SCN9A (0.51) | PTGDR2LMNATSHRALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050284-A1 | PYRAZOLYLPYRIDINE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | disclosed |