Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR2 | O43603 | 1/20 | 0.43 |
| ▸ | GALR1 | P47211 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | F13A1 | P00488 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22650491 | 0.86 | NR1H2 (0.46) | LMNANR1H2MAPTALDH1A1ENPP2 | |
| SCHEMBL1583728 | 0.86 | ESR2 (0.44) | LMNANR1H2MAPTALDH1A1ENPP2 | |
| SCHEMBL3312798 | 0.85 | MAPT (0.45) | LMNAPDE4BNR1H2MAPTALDH1A1 | |
| SCHEMBL31342592 | 0.84 | SUV39H2 (0.44) | LMNANR1H2MAPTALDH1A1ALK | |
| SCHEMBL25088458 | 0.83 | ENPP2 (0.43) | LMNANR1H2MAPTALDH1A1ENPP2 | |
| SCHEMBL1663317 | 0.83 | NR1H2 (0.40) | GALR2GALR1PDE4BNR1H2MAPT | |
| SCHEMBL1663277 | 0.83 | PTGDR2 (0.49) | LMNAHPGDTSHRALDH1A1ABHD6 | |
| SCHEMBL31347224 | 0.83 | MAPT (0.50) | LMNANR1H2MAPTALDH1A1ENPP2 | |
| SCHEMBL31195734 | 0.82 | ALK (0.55) | GALR2GALR1LMNAMAPTALDH1A1 | |
| SCHEMBL1583532 | 0.82 | P2RX7 (0.51) | LMNANR1H2MAPTALDH1A1ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050284-A1 | PYRAZOLYLPYRIDINE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | disclosed |