Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | RBP4 | P02753 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1663277 | 0.85 | PTGDR2 (0.49) | PTGDR2CYP2C19LMNAHPGDTSHR | |
| SCHEMBL1662724 | 0.84 | CPS1 (0.44) | PTGDR2P2RX7SCN9ASCN10AMAPT | |
| SCHEMBL1662800 | 0.83 | PTGDR2 (0.44) | PTGDR2RBP4P2RX7SCN9ASCN10A | |
| SCHEMBL1662961 | 0.82 | P2RX7 (0.42) | PTGDR2P2RX7SCN9ASCN10AMAPT | |
| SCHEMBL1663317 | 0.81 | NR1H2 (0.40) | FFAR4RBP4P2RX7SCN9AMAPT | |
| SCHEMBL1583489 | 0.80 | SCN9A (0.51) | PTGDR2P2RX7SCN9ASCN10AMAPT | |
| SCHEMBL1583807 | 0.78 | HRH3 (0.42) | PTGDR2P2RX7MEN1CYP2C9KMT2A | |
| SCHEMBL1583729 | 0.75 | PTGDR2 (0.39) | PTGDR2P2RX7SCN9ASCN10AMAPT | |
| SCHEMBL3654102 | 0.75 | P2RX7 (0.51) | P2RX7MEN1KMT2AALDH1A1 | |
| SCHEMBL1583535 | 0.75 | HRH3 (0.49) | P2RX7HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050284-A1 | PYRAZOLYLPYRIDINE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | disclosed |