SCHEMBL1663287

SCHEMBL1663287

CCOC(=O)c1ccc(C(C)(Br)c2ccc(C(=O)OCC)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.61
CA2 P00918 3/20 0.61
CA12 O43570 2/20 0.61
CA7 P43166 2/20 0.61
CA9 Q16790 2/20 0.61
CA14 Q9ULX7 2/20 0.61
ESR1 P03372 1/20 0.61
ESR2 Q92731 1/20 0.61
LMNA P02545 1/20 0.59
CYP1A2 P05177 1/20 0.59
CYP3A4 P08684 1/20 0.59
MAOA P21397 1/20 0.59
HPGD P15428 4/20 0.53
HTT P42858 2/20 0.53
NPC1 O15118 5/20 0.51
RAB9A P51151 5/20 0.51
SMN1; SMN2 Q16637 3/20 0.51
GAA P10253 1/20 0.51
MAPT P10636 3/20 0.50
MEN1 O00255 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL571045 0.87 CA12 (0.63) CA1CA2CA12CA7CA9
SCHEMBL2888233 0.87 CA1 (0.63) CA1CA2CA12CA7CA9
SCHEMBL547515 0.85 CA1 (0.61) CA1CA2CA12CA7CA9
SCHEMBL87450 0.84 CA1 (0.83) CA1CA2CA12CA7CA9
SCHEMBL19331900 0.84 LMNA (0.62) CA1CA2CA12CA7CA9
SCHEMBL5708223 0.84 LMNA (0.62) CA1CA2CA12CA7CA9
SCHEMBL13930900 0.84 CA1 (0.59) CA1CA2CA12CA7CA9
SCHEMBL1742368 0.84 CA12 (0.59) CA1CA2CA12CA7CA9
SCHEMBL1790586 0.84 CA1 (0.59) CA1CA2CA12CA7CA9
SCHEMBL9781670 0.83 LMNA (0.67) CA1CA2CA12CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1923418-B1 STAR POLYMER AND PROCESS FOR PRODUCTION THEREOF NIPPON SODA CO (JP) 2016-11-09 EP disclosed
EP-2311900-B1 Star polymer and method for producing the same NIPPON SODA CO (JP) 2015-03-11 EP disclosed
US-8436103-B2 Star polymer and method of producing the same NIPPON SODA CO., LTD. (JP) 2013-05-07 US disclosed
EP-2311900-A1 Star polymer and method for producing the same Nippon Soda Co., Ltd. (JP) 2011-04-20 EP disclosed
US-20090118436-A1 Star Polymer and Method of Producing the Same NIPPON SODA CO., LTD. (JP) 2009-05-07 US disclosed
EP-1923418-A1 STAR POLYMER AND PROCESS FOR PRODUCTION THEREOF NIPPON SODA CO., LTD. (JP) 2008-05-21 EP disclosed