SCHEMBL571045

SCHEMBL571045

CCOC(=O)c1ccc(C(C)(C)C)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.63
CA1 P00915 2/20 0.63
CA2 P00918 2/20 0.63
CA7 P43166 2/20 0.63
CA9 Q16790 2/20 0.63
CA14 Q9ULX7 2/20 0.63
ESR1 P03372 1/20 0.63
ESR2 Q92731 1/20 0.63
LMNA P02545 2/20 0.61
CYP1A2 P05177 1/20 0.61
CYP3A4 P08684 1/20 0.61
MAOA P21397 1/20 0.61
MAPT P10636 4/20 0.55
TP53 P04637 1/20 0.55
HPGD P15428 4/20 0.54
HTT P42858 2/20 0.54
NPC1 O15118 4/20 0.53
RAB9A P51151 4/20 0.53
SMN1; SMN2 Q16637 4/20 0.53
GAA P10253 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19357359 0.92 CA12 (0.54) CA12CA1CA2CA7CA9
SCHEMBL9425628 0.90 RARB (0.61) CA12CA1CA2CA7CA9
SCHEMBL2888233 0.89 CA1 (0.63) CA12CA1CA2CA7CA9
SCHEMBL9645677 0.87 RAB9A (0.74) LMNAMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL547515 0.87 CA1 (0.61) CA12CA1CA2CA7CA9
SCHEMBL1663287 0.87 CA1 (0.61) CA12CA1CA2CA7CA9
SCHEMBL5456918 0.86 HDAC1 (0.52) CA1CA2ESR1LMNACYP1A2
SCHEMBL87450 0.85 CA1 (0.83) CA12CA1CA2CA7CA9
SCHEMBL1742368 0.85 CA12 (0.59) CA12CA1CA2CA7CA9
SCHEMBL21672265 0.85 ALDH1A1 (0.66) CA1CA2ESR1LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 309 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12240925-B2 Process for preparing solid catalyst components for olefin polymerization W. R. GRACE & CO.- CONN. (US) 2025-03-04 US claimed
CN-118909169-A Solid catalyst component for olefin polymerization reaction, preparation method and application thereof 中国石油化工股份有限公司 2024-11-08 CN claimed
CN-116023243-B Preparation method of avobenzone 黄冈美丰化工科技有限公司 2024-05-24 CN claimed
CN-118026829-A Preparation method of avobenzone 黄冈美丰化工科技有限公司 2024-05-14 CN claimed
CN-116023243-A Preparation method of avobenzone 黄冈美丰化工科技有限公司 2023-04-28 CN claimed
US-20220289881-A1 PROCESS FOR PREPARING SOLID CATALYST COMPONENTS FOR OLEFIN POLYMERIZATION W. R. GRACE & CO.-CONN. (US) 2022-09-15 US claimed
CN-108929246-B Method for preparing hydroximic acid derivatives by solid-state method 湖南中医药大学 2021-07-02 CN claimed
EP-3710159-A1 CATALYST COMPONENTS FOR PROPYLENE POLYMERIZATION W. R. Grace & Co. - Conn. (US) 2020-09-23 EP claimed
CN-111479627-A Catalyst component for propylene polymerization 格雷斯公司 2020-07-31 CN claimed
EP-1771485-B1 HIGH ACTIVITY AND GOOD HYDROGEN RESPONSE ZIEGLER-NATTA POLYETHYLENE CATALYST ENGELHARD CORP (US) 2014-04-30 EP claimed
EP-1771485-A1 HIGH ACTIVITY AND GOOD HYDROGEN RESPONSE ZIEGLER-NATTA POLYETHYLENE CATALYST Engelhard Corporation (US) 2007-04-11 EP claimed
US-7153803-B2 High activity and good hydrogen response Ziegler-Natta polyethylene catalyst ENGELHARD CORPORATION (US) 2006-12-26 US claimed
WO-2006012111-A1 HIGH ACTIVITY AND GOOD HYDROGEN RESPONSE ZIEGLER-NATTA POLYETHYLENE CATALYST ENGELHARD CORPORATION (US) 2006-02-02 WO claimed
US-20050288460-A1 High activity and good hydrogen response Ziegler-Natta polyethylene catalyst W. R. GRACE & CO.-CONN. 2005-12-29 US claimed
US-6887817-B2 Olefin polymerization catalyst and process for preparing polyolefins using said catalyst FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2005-05-03 US claimed
US-20040039139-A1 Olefin polymerization catalyst and process for preparing polyolefins using said catalyst FORMOSA PLASTICS CO., U.S.A. 2004-02-26 US claimed
US-20030069372-A1 Olefin polymerization catalyst and process for preparing polyolefins with said catalyst FORMOSA PLASTICS CORPORATION, U.S.A. 2003-04-10 US claimed
EP-0067525-B1 A method for making a thermoplastic elastomer UNIROYAL CHEMICAL COMPANY, Inc. (US) 1989-11-23 EP claimed
US-4491652-A ETHYLENE-PROPLENE COPOLYMER, TITANIUM, MAGNESIUM, ALUMINUM CATALYST UNIROYAL, INC. (US) 1985-01-01 US claimed
EP-0067525-A2 A method for making a thermoplastic elastomer UNIROYAL CHEMICAL COMPANY, Inc. (US) 1982-12-22 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12240925-B2 Process for preparing solid catalyst components for olefin polymerization POF1B, PPOX, OGFOD1 CA12 789/4885CA1 436/4885CA2 645/4885
US-20220289881-A1 PROCESS FOR PREPARING SOLID CATALYST COMPONENTS FOR OLEFIN POLYMERIZATION POF1B, PPOX, OGFOD1 CA12 789/4885CA1 436/4885CA2 645/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.