Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 9/20 | 0.56 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MT-CO2 | P00403 | 2/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1664928 | 0.95 | HPGDS (0.55) | HPGDSGRM1EGFRRAB9AALDH1A1 | |
| SCHEMBL1663366 | 0.94 | HPGDS (0.54) | HPGDSGRM1RAB9A | |
| SCHEMBL1667509 | 0.94 | HPGDS (0.54) | HPGDSGRM1RAB9A | |
| SCHEMBL1664868 | 0.90 | HPGDS (0.57) | HPGDSEGFRRAB9AALDH1A1PDE7A | |
| SCHEMBL1664362 | 0.89 | HPGDS (0.56) | HPGDSGRM1EGFRRAB9AALDH1A1 | |
| SCHEMBL1666155 | 0.87 | HPGDS (0.56) | HPGDSGRM1EGFRPDE7A | |
| SCHEMBL1664686 | 0.86 | HPGDS (0.54) | HPGDSEGFRALDH1A1PDE7A | |
| SCHEMBL1664676 | 0.86 | HPGDS (0.54) | HPGDSEGFRRAB9APDE7A | |
| SCHEMBL1664557 | 0.86 | HPGDS (0.54) | HPGDSEGFRRAB9APDE7A | |
| SCHEMBL1664929 | 0.86 | HPGDS (0.55) | HPGDSGRM1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2642994-A2 | USE OF HEMATOPOIETIC GROWTH FACTOR MIMETICS | Ligand Pharmaceuticals Incorporated (US) | 2013-10-02 | — | — | EP | disclosed |
| EP-2488486-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | Ligand Pharmaceuticals Inc. (US) | 2012-08-22 | — | — | EP | disclosed |
| WO-2012068406-A2 | USE OF HEMATOPOIETIC GROWTH FACTOR MIMETICS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2012-05-24 | — | — | WO | disclosed |
| WO-2011046954-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2011-04-21 | — | — | WO | disclosed |