Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.30 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16633956 | 1.00 | OPRM1 (0.40) | OPRM1ACE2PTPN1HIF1AEPAS1 | |
| SCHEMBL16633957 | 1.00 | OPRM1 (0.40) | OPRM1ACE2PTPN1HIF1AEPAS1 | |
| SCHEMBL30665029 | 1.00 | OPRM1 (0.40) | OPRM1ACE2PTPN1HIF1AEPAS1 | |
| Methyl Piperitol SCHEMBL3032662 | 0.80 | OPRM1 (0.37) | OPRM1ACE2PTPN1 | |
| SCHEMBL7126607 | 0.75 | PTPN1 (0.38) | OPRM1ACE2PTPN1EPAS1 | |
| SCHEMBL1172762 | 0.75 | PTPN1 (0.38) | OPRM1ACE2PTPN1EPAS1 | |
| SCHEMBL8449154 | 0.72 | OPRM1 (0.38) | OPRM1ACE2PTPN1HIF1AEPAS1 | |
| SCHEMBL25227238 | 0.71 | OPRM1 (0.47) | OPRM1ACE2 | |
| SCHEMBL18878241 | 0.70 | OPRM1 (0.39) | OPRM1ACE2PTPN1HIF1AEPAS1 | |
| SCHEMBL29322977 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3005884-B1 | TASTE MODULATOR AND METHOD OF USE THEREOF | INT FLAVORS & FRAGRANCES INC (US) | 2017-04-19 | — | — | EP | disclosed |
| EP-3005884-A1 | TASTE MODULATOR AND METHOD OF USE THEREOF | International Flavors & Fragrances Inc. (US) | 2016-04-13 | — | — | EP | disclosed |
| US-20150104398-A1 | TASTE MODULATOR AND METHOD OF USE THEREOF | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2015-04-16 | — | — | US | disclosed |