SCHEMBL8449154

SCHEMBL8449154

CCO[Si](OCC)(OCC)C1C=C(C)CCC1C(C)C

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.38
ACE2 Q9BYF1 1/20 0.38
PTPN1 P18031 1/20 0.32
HIF1A Q16665 3/20 0.31
EPAS1 Q99814 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16633956 0.72 OPRM1 (0.40) OPRM1ACE2PTPN1HIF1AEPAS1
SCHEMBL16633957 0.72 OPRM1 (0.40) OPRM1ACE2PTPN1HIF1AEPAS1
SCHEMBL30665029 0.72 OPRM1 (0.40) OPRM1ACE2PTPN1HIF1AEPAS1
SCHEMBL16633959 0.72 OPRM1 (0.40) OPRM1ACE2PTPN1HIF1AEPAS1
SCHEMBL29365925 0.69 HIF1A (0.45) OPRM1ACE2PTPN1HIF1AEPAS1
SCHEMBL1301000 0.69 HIF1A (0.45) OPRM1ACE2PTPN1HIF1AEPAS1
SCHEMBL29121118 0.69 OPRM1 (0.38) OPRM1ACE2PTPN1HIF1AEPAS1
SCHEMBL1301004 0.69 HIF1A (0.45) OPRM1ACE2PTPN1HIF1AEPAS1
SCHEMBL31005385 0.69 HIF1A (0.45) OPRM1ACE2PTPN1HIF1AEPAS1
SCHEMBL1245098 0.69 HIF1A (0.45) OPRM1ACE2PTPN1HIF1AEPAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0234024-B2 Aqueous systems containing silanes for rendering masonry surfaces water repellant PCR GROUP INC (US) 1999-03-24 EP claimed