Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 6/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29277951 | 0.87 | KDM4E (0.39) | ELANEEGFRMAPTALDH1A1NPSR1 | |
| SCHEMBL23905478 | 0.86 | ELANE (0.38) | ELANEEGFRMAPTALDH1A1NPSR1 | |
| SCHEMBL3686647 | 0.86 | EGFR (0.40) | ELANEEGFRMAPTALDH1A1NPSR1 | |
| SCHEMBL1662993 | 0.82 | ALDH1A1 (0.47) | ELANEEGFRMAPTALDH1A1CYP2C9 | |
| SCHEMBL1663705 | 0.81 | SPR (0.34) | ELANEEGFRMAPTALDH1A1NPSR1 | |
| SCHEMBL29277955 | 0.79 | ELANE (0.38) | ELANEEGFRMAPTALDH1A1NPSR1 | |
| SCHEMBL3686649 | 0.78 | ELANE (0.39) | ELANEEGFRMAPTALDH1A1NPSR1 | |
| SCHEMBL30230692 | 0.75 | ELANE (0.44) | ELANEMAPTALDH1A1NPSR1CYP2C9 | |
| SCHEMBL1663185 | 0.75 | CA1 (0.33) | ALDH1A1TSHR | |
| SCHEMBL29155775 | 0.74 | ELANE (0.34) | ELANEEGFRMAPTALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050284-A1 | PYRAZOLYLPYRIDINE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | disclosed |