SCHEMBL16634158

SCHEMBL16634158

Oc1cccc(-n2ncc3ccccc32)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 3/20 0.51
PGR P06401 1/20 0.51
CYP11B2 P19099 2/20 0.50
CYP11B1 P15538 1/20 0.50
FGFR1 P11362 1/20 0.46
LRRK2 Q5S007 1/20 0.46
MAPK8 P45983 1/20 0.42
MAPK10 P53779 1/20 0.42
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
MGAM O43451 1/20 0.40
GAA P10253 1/20 0.40
SI P14410 1/20 0.40
MGAM2 Q2M2H8 1/20 0.40
KHK P50053 2/20 0.40
HPGD P15428 1/20 0.40
OPRD1 P41143 1/20 0.40
KDM4E B2RXH2 1/20 0.39
NPC1 O15118 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30186312 1.00 NR3C1 (0.51) NR3C1PGRCYP11B2CYP11B1FGFR1
SCHEMBL18289070 0.82 NR3C1 (0.68) NR3C1PGRKHKOPRD1IRAK4
SCHEMBL1880811 0.81 NR3C1 (0.55) NR3C1PGRCYP11B2CYP11B1FGFR1
SCHEMBL29399064 0.81 NR3C1 (0.55) NR3C1PGRCYP11B2CYP11B1FGFR1
SCHEMBL16719501 0.80 NR3C1 (0.43) NR3C1PGRCYP11B2CYP11B1FGFR1
SCHEMBL16720291 0.80 NR3C1 (0.46) NR3C1PGRCYP11B2CYP11B1FGFR1
SCHEMBL18289116 0.80 CYP11B2 (0.47) NR3C1CYP11B2CYP11B1LRRK2MAPK8
SCHEMBL2627244 0.80 IRAK4 (0.53) CYP11B2CYP11B1LRRK2MAPK8MAPK10
SCHEMBL2548808 0.80 KHK (0.56) NR3C1CYP11B2CYP11B1LRRK2MAPK8
SCHEMBL30918020 0.80 CYP11B2 (0.54) NR3C1PGRCYP11B2CYP11B1LRRK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035398-A1 TETRADENTATE AND OCTAHEDRAL METAL COMPLEXES CONTAINING NAPHTHYRIDINOCARBAZOLE AND ITS ANALOGUES UNIV ARIZONA STATE (US) 2026-02-05 US disclosed
US-12312366-B2 Tetradentate and octahedral metal complexes containing naphthyridinocarbazole and its analogues ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2025-05-27 US disclosed
US-12167676-B2 Platinum complexes and devices ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2024-12-10 US disclosed
US-20230115701-A1 TETRADENTATE AND OCTAHEDRAL METAL COMPLEXES CONTAINING NAPHTHYRIDINOCARBAZOLE AND ITS ANALOGUES UNIV ARIZONA STATE (US) 2023-04-13 US disclosed
US-20230115701-A1 TETRADENTATE AND OCTAHEDRAL METAL COMPLEXES CONTAINING NAPHTHYRIDINOCARBAZOLE AND ITS ANALOGUES UNIV ARIZONA STATE (US) 2023-04-13 US disclosed
US-11472827-B2 Tetradentate and octahedral metal complexes containing naphthyridinocarbazole and its analogues ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2022-10-18 US disclosed
US-20220069242-A1 PLATINUM COMPLEXES AND DEVICES UNIV ARIZONA STATE (US) 2022-03-03 US disclosed
US-11189808-B2 Platinum complexes and devices ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2021-11-30 US disclosed
US-11189808-B2 Platinum complexes and devices ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2021-11-30 US disclosed
CN-112794870-A Platinum complexes and devices 代表亚利桑那大学的亚利桑那校董事会 2021-05-14 CN disclosed
US-20170012224-A1 PLATINUM COMPLEXES AND DEVICES ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2017-01-12 US disclosed
US-20170012224-A1 PLATINUM COMPLEXES AND DEVICES ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2017-01-12 US disclosed
US-20160359125-A1 TETRADENTATE AND OCTAHEDRAL METAL COMPLEXES CONTAINING NAPHTHYRIDINOCARBAZOLE AND ITS ANALOGUES ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2016-12-08 US disclosed
US-20160359125-A1 TETRADENTATE AND OCTAHEDRAL METAL COMPLEXES CONTAINING NAPHTHYRIDINOCARBAZOLE AND ITS ANALOGUES ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2016-12-08 US disclosed
US-9385329-B2 Platinum complexes and devices Arizona Board of Regents on behalf of Arizona State University and Universal Display Corporation (US) 2016-07-05 US disclosed
US-9385329-B2 Platinum complexes and devices Arizona Board of Regents on behalf of Arizona State University and Universal Display Corporation (US) 2016-07-05 US disclosed
US-9385329-B2 Platinum complexes and devices Arizona Board of Regents on behalf of Arizona State University and Universal Display Corporation (US) 2016-07-05 US disclosed
US-20150105556-A1 PLATINUM COMPLEXES AND DEVICES ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2015-04-16 US disclosed
US-20150105556-A1 PLATINUM COMPLEXES AND DEVICES ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2015-04-16 US disclosed
US-20150105556-A1 PLATINUM COMPLEXES AND DEVICES ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2015-04-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11189808-B2 Platinum complexes and devices OXA1L, OCIAD1, OCIAD2 NR3C1 2821/4885PGR 692/4885CYP11B2 367/4885
US-20260035398-A1 TETRADENTATE AND OCTAHEDRAL METAL COMPLEXES CONTAINING NAPHTHYRIDINOCARBAZOLE AND ITS ANALOGUES LBR, SCO2, RAD54L NR3C1 150/4885PGR 2361/4885CYP11B2 2385/4885
US-20230115701-A1 TETRADENTATE AND OCTAHEDRAL METAL COMPLEXES CONTAINING NAPHTHYRIDINOCARBAZOLE AND ITS ANALOGUES PAICS, DNTT, PNPO NR3C1 2547/4885PGR 3635/4885CYP11B2 3148/4885
US-12312366-B2 Tetradentate and octahedral metal complexes containing naphthyridinocarbazole and its analogues PAICS, DNTT, PNPO NR3C1 2547/4885PGR 3635/4885CYP11B2 3148/4885
US-11472827-B2 Tetradentate and octahedral metal complexes containing naphthyridinocarbazole and its analogues PAICS, DNTT, PNPO NR3C1 2547/4885PGR 3635/4885CYP11B2 3148/4885
US-12167676-B2 Platinum complexes and devices OXA1L, OCIAD1, OCIAD2 NR3C1 2821/4885PGR 692/4885CYP11B2 367/4885
US-20170012224-A1 PLATINUM COMPLEXES AND DEVICES OXA1L, OCIAD1, OCIAD2 NR3C1 2821/4885PGR 692/4885CYP11B2 367/4885
US-20220069242-A1 PLATINUM COMPLEXES AND DEVICES OXA1L, OCIAD1, OCIAD2 NR3C1 2821/4885PGR 692/4885CYP11B2 367/4885
US-20160359125-A1 TETRADENTATE AND OCTAHEDRAL METAL COMPLEXES CONTAINING NAPHTHYRIDINOCARBAZOLE AND ITS ANALOGUES PAICS, DNTT, PNPO NR3C1 2547/4885PGR 3635/4885CYP11B2 3148/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.