Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.34 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.34 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9175685 | 0.81 | CYP2C9 (0.54) | CYP2C9CYP2C19TDP1PRMT3CARM1 | |
| SCHEMBL16633974 | 0.81 | PAOX (0.38) | CYP2C9CYP2C19PAOXALDH1A1SMN1; SMN2 | |
| SCHEMBL28438294 | 0.78 | CYP2C9 (0.47) | CYP2C9CYP2C19TDP1PRMT3CARM1 | |
| SCHEMBL3270169 | 0.78 | ALDH1A1 (0.43) | TDP1KDM4EALDH1A1SMN1; SMN2CA2 | |
| SCHEMBL2866750 | 0.77 | CA12 (0.48) | CYP2C9CYP2C19TDP1PAOXKDM4E | |
| SCHEMBL3270353 | 0.77 | PAOX (0.42) | CYP2C19PAOXALDH1A1MEN1KMT2A | |
| SCHEMBL8083063 | 0.76 | CYP2C9 (0.48) | CYP2C9CYP2C19TDP1PRMT3CARM1 | |
| SCHEMBL12191368 | 0.75 | CA12 (0.48) | CYP2C9CYP2C19TDP1PAOXKDM4E | |
| SCHEMBL12191358 | 0.75 | CA12 (0.48) | CYP2C9CYP2C19TDP1PAOXKDM4E | |
| SCHEMBL30925269 | 0.75 | CA12 (0.50) | CYP2C9CYP2C19TDP1PAOXALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9427698-B2 | Amino-siloxane composition and methods of using the same | GENERAL ELECTRIC COMPANY (US) | 2016-08-30 | — | — | US | disclosed |
| US-20150104366-A1 | AMINO-SILOXANE COMPOSITION AND METHODS OF USING THE SAME | GENERAL ELECTRIC COMPANY (US) | 2015-04-16 | — | — | US | disclosed |