Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16634396 | 0.81 | CYP2C9 (0.48) | PAOXSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL7898955 | 0.80 | PAOX (0.37) | PAOXSMN1; SMN2CHRM2 | |
| SCHEMBL3270633 | 0.80 | ALDH1A1 (0.32) | MEN1KMT2AALDH1A1 | |
| SCHEMBL3270353 | 0.78 | PAOX (0.42) | PAOXMEN1KMT2AALDH1A1CYP2C19 | |
| SCHEMBL28356688 | 0.78 | PAOX (0.38) | PAOXSMN1; SMN2CHRM2MEN1KMT2A | |
| SCHEMBL11323396 | 0.77 | PAOX (0.48) | PAOXCHRM2MEN1KMT2ALMNA | |
| SCHEMBL7994712 | 0.75 | PAOX (0.57) | PAOXCHRM2MEN1KMT2ALMNA | |
| SCHEMBL229973 | 0.74 | PAOX (0.43) | PAOXMEN1KMT2ALMNANPSR1 | |
| SCHEMBL2866750 | 0.74 | CA12 (0.48) | PAOXSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL10814957 | 0.73 | TSHR (0.50) | PAOXCHRM2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9427698-B2 | Amino-siloxane composition and methods of using the same | GENERAL ELECTRIC COMPANY (US) | 2016-08-30 | — | — | US | disclosed |
| US-20150104366-A1 | AMINO-SILOXANE COMPOSITION AND METHODS OF USING THE SAME | GENERAL ELECTRIC COMPANY (US) | 2015-04-16 | — | — | US | disclosed |