SCHEMBL16634411

SCHEMBL16634411

c1ccc2c(-c3ccc(Oc4ccc(-c5cccc6ccccc56)cc4)cc3)cccc2c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 9/20 0.55
PPARA Q07869 9/20 0.55
CYP2C9 P11712 2/20 0.55
CYP2C19 P33261 2/20 0.55
PPARD Q03181 1/20 0.55
CHRNB4 P30926 1/20 0.53
CHRNA3 P32297 1/20 0.53
CHRNA7 P36544 1/20 0.53
CA12 O43570 3/20 0.51
CA1 P00915 3/20 0.51
CA2 P00918 3/20 0.51
CA9 Q16790 3/20 0.51
HDAC8 Q9BY41 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
ENPP3 O14638 1/20 0.47
ENPP1 P22413 1/20 0.47
GSTP1 P09211 1/20 0.47
MCL1 Q07820 1/20 0.44
ACMSD Q8TDX5 1/20 0.44
CYP1A2 P05177 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1178233 0.91 NCOA1 (0.53) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL21882470 0.88 PPARG (0.50) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL3798335 0.87 CA12 (0.62) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL30122908 0.84 CA12 (0.66) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL10304762 0.84 PPARG (0.53) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL1890032 0.84 PPARG (0.56) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL14244467 0.82 PPARG (0.51) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL590640 0.82 PPARG (0.51) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL316112 0.82 TNF (0.57) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL21882406 0.81 MEN1 (0.43) PPARGPPARACYP2C9CYP2C19PPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116354891-B Naphthyl phenyl ether compound, and preparation method and application thereof 河南省锐达医药科技有限公司 2025-01-07 CN claimed
CN-116829527-A Naphthyl phenyl ether compound and lubricating oil composition containing the same 株式会社MORESCO 2023-09-29 CN claimed
CN-116354891-A Naphthyl phenyl ether compound, and preparation method and application thereof 河南省锐达医药科技有限公司 2023-06-30 CN claimed
WO-2022172934-A1 NAPHTHYL PHENYL ETHER COMPOUND AND LUBRICANT COMPOSITION CONTAINING SAME 株式会社MORESCO 2022-08-18 WO claimed
EP-4596645-A1 COATING COMPOSITION FOR ENDOSCOPES, LUBRICATION MEMBER FOR ENDOSCOPES, METHOD FOR PRODUCING LUBRICATION MEMBER FOR ENDOSCOPES, FLEXIBLE TUBE FOR ENDOSCOPES, AND ENDOSCOPE FUJIFILM Corporation (JP) 2025-08-06 EP disclosed
CN-116829527-B Naphthyl phenyl ether compound and lubricating oil composition containing the same 株式会社MORESCO 2025-08-01 CN disclosed
US-20250205395-A1 COATING COMPOSITION FOR ENDOSCOPE, LUBRICATING MEMBER FOR ENDOSCOPE, METHOD FOR MANUFACTURING LUBRICATING MEMBER FOR ENDOSCOPE, FLEXIBLE TUBE FOR ENDOSCOPE, AND ENDOSCOPE FUJIFILM CORPORATION (JP) 2025-06-26 US disclosed
CN-118891302-A Epoxy resin, cured product of epoxy resin, and method for producing epoxy resin 积水化学工业株式会社 2024-11-01 CN disclosed
WO-2024071044-A1 COATING COMPOSITION FOR ENDOSCOPES, LUBRICATION MEMBER FOR ENDOSCOPES, METHOD FOR PRODUCING LUBRICATION MEMBER FOR ENDOSCOPES, FLEXIBLE TUBE FOR ENDOSCOPES, AND ENDOSCOPE 富士フイルム株式会社 2024-04-04 WO disclosed
CN-116829527-A Naphthyl phenyl ether compound and lubricating oil composition containing the same 株式会社MORESCO 2023-09-29 CN disclosed
CN-116829527-A Naphthyl phenyl ether compound and lubricating oil composition containing the same 株式会社MORESCO 2023-09-29 CN disclosed
WO-2023182522-A1 EPOXY RESIN, CURED BODY OF SAME AND METHOD FOR PRODUCING EPOXY RESIN 積水化学工業株式会社 2023-09-28 WO disclosed
CN-104602807-B Catalyst and process for dehydration of alcohols 陶氏环球技术有限责任公司 2017-12-26 CN disclosed
CN-104271544-B Aryl alcohol catalytic dehydration is into diaryl ether 陶氏环球技术有限责任公司 2017-12-26 CN disclosed
CN-103998408-B Process for the dehydration of alcohols DOW GLOBAL TECHNOLOGIES LLC (US) 2016-01-20 CN disclosed
CN-104602807-A Catalyst and process for dehydration of alcohols DOW GLOBAL TECHNOLOGIES INC 2015-05-06 CN disclosed
CN-104582837-A Catalysts and methods for alcohol dehydration DOW GLOBAL TECHNOLOGIES LLC 2015-04-29 CN disclosed
US-20150105351-A1 COMPOUNDS AND METHODS FOR TREATING HIV INFECTIONS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2015-04-16 US disclosed
CN-104364226-A Catalytic dehydration of aryl alcohols to diaryl ethers DOW GLOBAL TECHNOLOGIES INC 2015-02-18 CN disclosed
CN-104271544-A Catalytic dehydration of aryl alcohols to diaryl ethers DOW GLOBAL TECHNOLOGIES INC 2015-01-07 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150105351-A1 COMPOUNDS AND METHODS FOR TREATING HIV INFECTIONS POLM, POLRMT, DHFR PPARG 4268/4885PPARA 4098/4885CYP2C9 1797/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.