Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.65 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | LPL | P06858 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CSK | P41240 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL732934 | 0.87 | TGM2 (0.81) | TGM2LMNAALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL16634483 | 0.81 | TGM2 (0.50) | TGM2TRPV1LMNALPLLIPG | |
| SCHEMBL2452377 | 0.80 | TGM2 (0.71) | TGM2LMNAALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL124217 | 0.80 | TGM2 (0.71) | TGM2TRPV1LMNAALDH1A1CYP2D6 | |
| SCHEMBL9179038 | 0.79 | TGM2 (0.69) | TGM2LMNAALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL5071229 | 0.79 | TGM2 (0.69) | TGM2LMNAALDH1A1CYP2C19 | |
| SCHEMBL4927519 | 0.79 | TGM2 (0.69) | TGM2LMNAALDH1A1CYP2C19TDP1 | |
| SCHEMBL2723387 | 0.79 | TGM2 (0.69) | TGM2LMNAALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL2722983 | 0.79 | TGM2 (0.74) | TGM2LMNAALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL8966436 | 0.79 | TGM2 (1.00) | TGM2LMNAALDH1A1CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10088476-B2 | Volume response sensors having analyte controlled reversible crosslinking | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2018-10-02 | — | — | US | disclosed |
| US-20160252505-A1 | VOLUME RESPONSE SENSORS HAVING ANALYTE CONTROLLED REVERSIBLE CROSSLINKING | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOI S (US) | 2016-09-01 | — | — | US | disclosed |
| WO-2015053975-A1 | VOLUME RESPONSE SENSORS HAVING CONTROLLED REVERSIBLE CROSSLINKING | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2015-04-16 | — | — | WO | disclosed |