Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23824810 | 0.98 | FFAR1 (0.49) | FFAR1ESR1ESR2NPC1RAB9A | |
| SCHEMBL15391386 | 0.98 | FFAR1 (0.49) | FFAR1ESR1ESR2NPC1RAB9A | |
| SCHEMBL9951576 | 0.94 | PPARG (0.49) | FFAR1ESR1ESR2KMT2AMEN1 | |
| SCHEMBL23824811 | 0.94 | PPARG (0.49) | FFAR1ESR1ESR2KMT2AMEN1 | |
| SCHEMBL28222075 | 0.94 | ESR1 (0.46) | ESR1ESR2NPC1RAB9AACACB | |
| SCHEMBL1509141 | 0.94 | ESR1 (0.46) | ESR1ESR2NPC1RAB9AACACB | |
| SCHEMBL28238207 | 0.92 | ESR1 (0.47) | FFAR1ESR1ESR2NPC1RAB9A | |
| SCHEMBL1936124 | 0.92 | ESR1 (0.47) | FFAR1ESR1ESR2NPC1RAB9A | |
| SCHEMBL19470216 | 0.88 | ACACB (0.49) | ESR1ESR2ACACBPPARGPPARA | |
| SCHEMBL248142 | 0.85 | PTGS2 (0.51) | ESR1NPC1RAB9AACACBLDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3099731-A1 | POLYSILOXANE-POLYCARBONATE BLOCK COCONDENSATES WITH IMPROVED RHEOLOGICAL PROPERTIES | Covestro Deutschland AG (DE) | 2016-12-07 | — | — | EP | disclosed |
| EP-3055341-A1 | PREPARATION OF SILOXANE-CONTAINING BLOCK COPOLYCARBONATES BY MEANS OF REACTIVE EXTRUSION | Covestro Deutschland AG (DE) | 2016-08-17 | — | — | EP | disclosed |
| EP-3055344-A1 | POLYSILOXANE-POLYCARBONATE BLOCK COCONDENSATES | Covestro Deutschland AG (DE) | 2016-08-17 | — | — | EP | disclosed |
| WO-2015113916-A1 | POLYSILOXANE-POLYCARBONATE BLOCK COCONDENSATES WITH IMPROVED RHEOLOGICAL PROPERTIES | BAYER MATERIALSCIENCE AG (DE) | 2015-08-06 | — | — | WO | disclosed |
| WO-2015052113-A1 | POLYSILOXANE-POLYCARBONATE BLOCK COCONDENSATES | BAYER MATERIALSCIENCE AG (DE) | 2015-04-16 | — | — | WO | disclosed |
| WO-2015052110-A1 | PREPARATION OF SILOXANE-CONTAINING BLOCK COPOLYCARBONATES BY MEANS OF REACTIVE EXTRUSION | BAYER MATERIALSCIENCE AG (DE) | 2015-04-16 | — | — | WO | disclosed |