SCHEMBL248142

SCHEMBL248142

CC(C)Cc1ccc(OC(=O)Oc2ccccc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 4/20 0.51
PTGS1 P23219 3/20 0.50
LMNA P02545 2/20 0.50
CYP2C9 P11712 2/20 0.50
AKR1C3 P42330 2/20 0.50
CXCR1 P25024 2/20 0.50
CXCR2 P25025 2/20 0.50
ALOX5 P09917 2/20 0.50
ALB P02768 1/20 0.50
ESR1 P03372 1/20 0.50
RARB P10826 1/20 0.50
ADRB3 P13945 1/20 0.50
NFKB1 P19838 1/20 0.50
HTR2A P28223 1/20 0.50
NR1I3 Q14994 1/20 0.50
SLC22A6 Q4U2R8 1/20 0.50
CXCL8 P10145 1/20 0.50
TSHR P16473 1/20 0.50
AKR1C2 P52895 1/20 0.50
BLM P54132 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL237613 0.93 PTGS2 (0.56) PTGS2PTGS1LMNACYP2C9AKR1C3
SCHEMBL237802 0.88 PTGS2 (0.52) PTGS2PTGS1LMNACYP2C9AKR1C3
SCHEMBL16634485 0.85 FFAR1 (0.48) PTGS2ESR1NPC1RAB9AACACB
SCHEMBL21517639 0.84 PTGS2 (0.55) PTGS2PTGS1LMNACYP2C9AKR1C3
SCHEMBL23824810 0.83 FFAR1 (0.49) PTGS2ESR1NPC1RAB9AACACB
SCHEMBL15391386 0.83 FFAR1 (0.49) PTGS2ESR1NPC1RAB9AACACB
SCHEMBL17236371 0.83 KMT2A (0.55) PTGS2PTGS1LMNACYP2C9AKR1C3
SCHEMBL1790172 0.83 MAPT (0.50) PTGS2PTGS1LMNACYP2C9AKR1C3
SCHEMBL28969727 0.82 TSHR (0.54) PTGS2TSHRPPARGPPARA
SCHEMBL28222075 0.82 ESR1 (0.46) ESR1TSHRNPC1RAB9AACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 257 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600116-B2 Special polymer layers for faster laminability of multilayer structures COVESTRO DEUTSCHLAND AG (DE) 2026-04-14 US disclosed
EP-3055342-B1 PROCESS FOR PREPARING POLYSILOXANE-POLYCARBONATE BLOCK COCONDENSATES USING A SALT OF A WEAK ACID COVESTRO DEUTSCHLAND AG (DE) 2026-03-04 EP disclosed
US-12365775-B2 Process for partial colouring of plastic parts using solid colourants in colour- carrier layers COVESTRO DEUTSCHLAND AG (DE) 2025-07-22 US disclosed
US-20250205963-A1 METHOD FOR PRODUCING A PLASTIC MOLDING tooz technologies GmbH (DE) 2025-06-26 US disclosed
EP-4549163-A2 IMPROVED METHOD FOR PARTIAL COLOURING OF PLASTIC PARTS Covestro Deutschland AG (DE) 2025-05-07 EP disclosed
EP-2593288-B2 APPARATUS AND PROCESS FOR PRODUCING PRODUCTS FROM PIGMENT-CONTAINING POLYMER MIXTURES COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2025-04-16 EP disclosed
US-20250091332-A1 FILM STRUCTURE SUITABLE FOR RAPID LAMINATION COVESTRO DEUTSCHLAND AG (DE) 2025-03-20 US disclosed
EP-3055344-B1 POLYSILOXANE-POLYCARBONATE BLOCK COCONDENSATES COVESTRO DEUTSCHLAND AG (DE) 2025-03-12 EP disclosed
EP-3840958-B1 IMPROVED METHOD FOR PARTIAL COLOURING OF PLASTIC PARTS COVESTRO DEUTSCHLAND AG (DE) 2025-02-19 EP disclosed
US-20240308191-A1 SPECIAL POLYMER LAYERS FOR FASTER LAMINABILITY OF MULTILAYER STRUCTURES COVESTRO DEUTSCHLAND AG (DE) 2024-09-19 US disclosed
US-20050054808-A1 Novel aromatic dihydroxy compound useful for the preparation of (CO)polycarbonates BAYER MATERIALSCIENCE AG (DE) 2005-03-10 US disclosed
US-6835797-B2 Reacting a dihydroxyaryl compound with a diaryl carbonate to obtain a melt; flash evaporation of the monohydroxyaryl compound; heating the melt under vacuum; and repeating the steps BAYER AKTIENGESELLSCHAFT (DE) 2004-12-28 US disclosed
US-20040158025-A1 Polycarbonates, polyester carbonates and polyesters having lateral, cycloalkyl-substituted phenols BAYER AKTIENGESELLSCHAFT (DE) 2004-08-12 US disclosed
US-20040127677-A1 Polycarbonates, polyester carbonates and polyesters having lateral, cycloalkyl-substituted phenols BAYER AKTIENGESELLSCHAFT (DE) 2004-07-01 US disclosed
US-6753405-B2 MORE THAN 35 MOLE % OF UNITS DERIVED FROM DIHYDROXYDIPHENYLENE AND THE REST FROM AN ALKYLIDENE OR CYCLOALKYLIDENE BISPHENOL; PREPARED BY MELT TRANSESTERIFICATION; USED TO PREPARE TRANSPARENT MOLDINGS BAYER AKTIENGESELLSCHAFT (DE) 2004-06-22 US disclosed
US-20040103717-A1 Process for the production of polycarbonate which is damaged to a particularly small extent by oxygen BAYER AKTIENGESELLSCHAFT (DE) 2004-06-03 US disclosed
US-20030055201-A1 Process for optimising the production of polycarbonate by melt transesterification BAYER AKTIENGESELLSCHAFT (DE) 2003-03-20 US disclosed
CN-1397582-A Prepn. of copolymer carbonic ester BAYER AG (DE) 2003-02-19 CN disclosed
US-20030027971-A1 Preparation of copolycarbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-02-06 US disclosed
US-20020137874-A1 Process for producing oligocarbonates COVESTRO DEUTSCHLAND AG (DE) 2002-09-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12600116-B2 Special polymer layers for faster laminability of multilayer structures ASH2L, SMC2, ELL PTGS2 1779/4885PTGS1 2617/4885LMNA 65/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.