Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | PTP4A3 | O75365 | 2/20 | 0.44 |
| ▸ | PTP4A1 | Q93096 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | PTP4A2 | Q12974 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | RHOA | P61586 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30940 | 0.84 | TSHR (0.59) | CYP3A4PTP4A3PTP4A1ALDH1A1TSHR | |
| Anthracene SCHEMBL10612288 | 0.82 | ALDH1A1 (0.69) | ALDH1A1TSHRMAPTNPSR1KDM4E | |
| Anthracene SCHEMBL11672628 | 0.78 | ALDH1A1 (0.46) | ALDH1A1TSHRMAPTKDM4EMEN1 | |
| SCHEMBL541021 | 0.78 | TSHR (0.52) | CYP3A4PTP4A3PTP4A1ALDH1A1TSHR | |
| Anthracene SCHEMBL16634640 | 0.77 | APP (0.46) | CYP3A4PTP4A3PTP4A1ALDH1A1TSHR | |
| Ether SCHEMBL540636 | 0.75 | TSHR (0.62) | CYP3A4PTP4A3PTP4A1ALDH1A1TSHR | |
| Propionic Acid SCHEMBL27993809 | 0.75 | TSHR (0.58) | CYP3A4PTP4A3PTP4A1ALDH1A1TSHR | |
| SCHEMBL7561802 | 0.73 | CYP3A4 (0.45) | CYP3A4ALDH1A1TSHRCASP1MAPT | |
| SCHEMBL11882529 | 0.73 | ALDH1A1 (0.57) | ALDH1A1TSHRMAPTMEN1KMT2A | |
| SCHEMBL10834421 | 0.73 | ALDH1A1 (0.50) | CYP3A4PTP4A3PTP4A1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9695286-B2 | Rubbery polysiloxanes carrying cyanoacrylate functions and related methods for their preparation and uses therefor | THE UNIVERSITY OF AKRON (US) | 2017-07-04 | — | — | US | disclosed |
| US-20160215098-A1 | RUBBERY POLYSILOXANES CARRYING CYANOACRYLATE FUNCTIONS AND RELATED METHODS FOR THEIR PREPARATION AND USES THEREFOR | THE UNIVERSITY OF AKRON (US) | 2016-07-28 | — | — | US | disclosed |
| WO-2015054357-A1 | RUBBERY POLYSILOXANES CARRYING CYANOACRYLATE FUNCTIONS AND RELATED METHODS FOR THEIR PREPARATION AND USES THEREFOR | THE UNIVERSITY OF AKRON (US) | 2015-04-16 | — | — | WO | disclosed |