Ether

Ether

SCHEMBL540636

C=CCOC(=O)C(=C)C#N.CCOCC

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.62
ALDH1A1 P00352 1/20 0.62
PTP4A3 O75365 2/20 0.36
PTP4A1 Q93096 2/20 0.36
PTP4A2 Q12974 1/20 0.36
THRB P10828 2/20 0.36
CYP2C9 P11712 1/20 0.36
TDP1 Q9NUW8 1/20 0.34
MAPT P10636 3/20 0.34
KDM4E B2RXH2 2/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
NPC1 O15118 1/20 0.34
USP2 O75604 1/20 0.34
LMNA P02545 1/20 0.34
TP53 P04637 1/20 0.34
GAA P10253 1/20 0.34
HPGD P15428 1/20 0.34
HTT P42858 1/20 0.34
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Ethoxyethanol SCHEMBL11500499 0.90 TSHR (0.54) TSHRALDH1A1PTP4A3PTP4A1PTP4A2
SCHEMBL30940 0.89 TSHR (0.59) TSHRALDH1A1PTP4A3PTP4A1PTP4A2
Propionic Acid SCHEMBL27993809 0.87 TSHR (0.58) TSHRALDH1A1PTP4A3PTP4A1PTP4A2
SCHEMBL541021 0.83 TSHR (0.52) TSHRALDH1A1PTP4A3PTP4A1PTP4A2
Ether SCHEMBL173935 0.79 THRB (0.58) TSHRALDH1A1THRBTDP1MAPT
Butadiene SCHEMBL10811584 0.79 ALDH1A1 (0.85) TSHRALDH1A1PTP4A1THRBCYP2C9
SCHEMBL828235 0.79 ALDH1A1 (0.71) TSHRALDH1A1THRBCYP2C9MAPT
SCHEMBL28761858 0.78 TSHR (0.53) TSHRALDH1A1PTP4A3PTP4A1PTP4A2
SCHEMBL6034773 0.78 ALDH1A1 (0.50) TSHRALDH1A1PTP4A3PTP4A1THRB
SCHEMBL1921912 0.78 TSHR (0.46) TSHRALDH1A1THRBCYP2C9MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3335738-B1 NEW TYPE CYANOACRYLATE MEDICAL ADHESIVE AND PREPARATION METHOD AND USE THEREOF SHEN WEI (CN) 2019-11-06 EP claimed
US-7932305-B2 Viscous α-cyanoacrylate compositions ETHICON, INC. (US) 2011-04-26 US claimed
US-20090326095-A1 Viscous alpha-Cyanoacrylate Compositions ETHICON, INC. 2009-12-31 US claimed
WO-2009158302-A2 VISCOUS ALPHA-CYANOACRYLATE COMPOSITIONS CLOSURE MEDICAL CORPORATION (US) 2009-12-30 WO claimed
EP-1317294-B1 ABSORBABLE ADHESIVE COMPOSITIONS CLOSURE MEDICAL CORP (US) 2005-03-16 EP claimed
EP-1317294-A1 ABSORBABLE ADHESIVE COMPOSITIONS Closure Medical Corporation (US) 2003-06-11 EP claimed
US-20020037310-A1 Absorbable adhesive compositions CLOSURE MEDICAL CORPORATION (US) 2002-03-28 US claimed
WO-2002009785-A1 ABSORBABLE ADHESIVE COMPOSITIONS CLOSURE MEDICAL CORPORATION (US) 2002-02-07 WO claimed
EP-3335738-B1 NEW TYPE CYANOACRYLATE MEDICAL ADHESIVE AND PREPARATION METHOD AND USE THEREOF SHEN WEI (CN) 2019-11-06 EP disclosed
EP-2089308-B1 DISPENSER ETHICON INC (US) 2018-12-26 EP disclosed
US-9642658-B2 Device and method for delivery of therapeutic agents via internal implants ORTHOCLIP LLC (US) 2017-05-09 US disclosed
EP-2629687-A1 DEVICE AND METHOD FOR DELIVERY OF THERAPEUTIC AGENTS VIA INTERNAL IMPLANTS Bioshape Solutions Inc. (US) 2013-08-28 EP disclosed
CN-101600643-B Dispenser CLOSURE MEDICAL CORP 2013-07-31 CN disclosed
US-8287202-B2 Method for dispensing a polymerizable monomer adhesive ETHICON, INC. (US) 2012-10-16 US disclosed
EP-1317294-A1 ABSORBABLE ADHESIVE COMPOSITIONS Closure Medical Corporation (US) 2003-06-11 EP disclosed
US-6547467-B2 Microapplicators, delivery systems and methods for adhesives and sealants CLOSURE MEDICAL CORPORATION 2003-04-15 US disclosed
WO-2003020358-A1 MICROAPPLICATORS, DELIVERY SYSTEMS AND METHODS FOR ADHESIVES AND SEALANTS CLOSURE MEDICAL CORPORATION (US) 2003-03-13 WO disclosed
US-20030044219-A1 MICROAPPLICATORS, DELIVERY SYSTEMS AND METHODS FOR ADHESIVES AND SEALANTS CLOSURE MEDICAL CORPORATION (US) 2003-03-06 US disclosed
US-20020037310-A1 Absorbable adhesive compositions CLOSURE MEDICAL CORPORATION (US) 2002-03-28 US disclosed
WO-2002009785-A1 ABSORBABLE ADHESIVE COMPOSITIONS CLOSURE MEDICAL CORPORATION (US) 2002-02-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020037310-A1 Absorbable adhesive compositions EPCAM, CDH1, ICAM1 TSHR 4471/4885ALDH1A1 178/4885PTP4A3 4597/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.