Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 7/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | MAPK3 | P27361 | 3/20 | 0.38 |
| ▸ | F13A1 | P00488 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TGM1 | P22735 | 1/20 | 0.37 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | VCP | P55072 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28900184 | 0.88 | TGM2 (0.44) | TGM2MAPK3F13A1LMNATGM1 | |
| SCHEMBL14750323 | 0.81 | BTK (0.46) | TGM2BTK | |
| SCHEMBL15356556 | 0.81 | ITK (0.43) | TGM2BTKJAK3F13A1LMNA | |
| SCHEMBL31162390 | 0.80 | TGM2 (0.58) | TGM2MAPK3LMNA | |
| SCHEMBL21894170 | 0.80 | TGM2 (0.58) | TGM2MAPK3LMNA | |
| SCHEMBL15279864 | 0.80 | ALDH1A1 (0.52) | LMNA | |
| SCHEMBL15359415 | 0.80 | TGM2 (0.41) | TGM2BTKJAK3F13A1LMNA | |
| SCHEMBL23293735 | 0.79 | TGM2 (0.47) | TGM2BTKJAK3MAPK3F13A1 | |
| SCHEMBL11508898 | 0.79 | TGM2 (0.61) | TGM2BTKJAK3F13A1LMNA | |
| SCHEMBL28900078 | 0.78 | TTR (0.45) | TGM2BTKJAK3F13A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10088476-B2 | Volume response sensors having analyte controlled reversible crosslinking | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2018-10-02 | — | — | US | disclosed |
| US-20160252505-A1 | VOLUME RESPONSE SENSORS HAVING ANALYTE CONTROLLED REVERSIBLE CROSSLINKING | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOI S (US) | 2016-09-01 | — | — | US | disclosed |
| WO-2015053975-A1 | VOLUME RESPONSE SENSORS HAVING CONTROLLED REVERSIBLE CROSSLINKING | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2015-04-16 | — | — | WO | disclosed |