Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 20/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16634653 | 0.88 | RORC (0.60) | RORCCYP2C9CYP3A4CYP2C19PPARG | |
| SCHEMBL16634596 | 0.87 | RORC (0.61) | RORCCYP2C9CYP3A4CYP2C19PPARG | |
| SCHEMBL16634652 | 0.85 | RORC (0.50) | RORCCYP2C9CYP3A4CYP2C19PPARG | |
| SCHEMBL16634616 | 0.82 | RORC (0.49) | RORCCYP2C9CYP3A4CYP2C19PPARG | |
| SCHEMBL16634697 | 0.81 | RORC (0.51) | RORCCYP2C9CYP3A4CYP2C19PPARG | |
| SCHEMBL16634636 | 0.81 | RORC (0.56) | RORCCYP2C9CYP3A4CYP2C19PPARG | |
| SCHEMBL16634618 | 0.80 | RORC (0.45) | RORCCYP2C9CYP3A4CYP2C19PPARG | |
| SCHEMBL16634775 | 0.79 | RORC (0.63) | RORCCYP2C9CYP3A4CYP2C19PPARG | |
| SCHEMBL16634647 | 0.76 | RORC (0.54) | RORCCYP2C9CYP3A4PPARG | |
| SCHEMBL16634781 | 0.76 | RORC (0.55) | RORCCYP2C9CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015052675-A1 | SUBSTITUTED DIHYDRO-BENZIMIDAZOLE COMPOUNDS AS ROR GAMMA MODULATORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2015-04-16 | — | — | WO | disclosed |