Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.54 |
| ▸ | AURKA | O14965 | 2/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | GABRP | O00591 | 2/20 | 0.45 |
| ▸ | GABRD | O14764 | 2/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.45 |
| ▸ | GABRE | P78334 | 2/20 | 0.45 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.45 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.45 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.45 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.45 |
| ▸ | B3GNT2 | Q9NY97 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11356818 | 0.87 | DAO (0.60) | DAOPGRGABRPGABRDGABRA1 | |
| SCHEMBL702708 | 0.83 | AURKA (0.54) | DAOAURKALMNASMN1; SMN2TSHR | |
| SCHEMBL16634744 | 0.80 | L3MBTL1 (0.55) | DAOAURKALMNASMN1; SMN2KDM4E | |
| SCHEMBL25430362 | 0.79 | PARP1 (0.48) | DAOAURKALMNASMN1; SMN2TSHR | |
| SCHEMBL30441384 | 0.79 | AURKA (0.58) | DAOAURKAPGRB3GNT2LMNA | |
| SCHEMBL11344894 | 0.78 | DAO (0.50) | DAOPGRGABRPGABRDGABRA1 | |
| SCHEMBL4252448 | 0.76 | SMN1; SMN2 (0.66) | LMNASMN1; SMN2FEN1KDM4EALDH1A1 | |
| SCHEMBL3831898 | 0.75 | AKT2 (0.51) | DAOAURKAPGRGABRPGABRD | |
| SCHEMBL8947417 | 0.73 | DAO (0.63) | DAOPGRGABRPGABRDGABRA1 | |
| SCHEMBL6840233 | 0.73 | AURKA (0.52) | DAOAURKAB3GNT2LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015052675-A1 | SUBSTITUTED DIHYDRO-BENZIMIDAZOLE COMPOUNDS AS ROR GAMMA MODULATORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2015-04-16 | — | — | WO | disclosed |