Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | AURKA | O14965 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TNKS | O95271 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | DAO | P14920 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAT2A | P31153 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29092672 | 0.86 | SMN1; SMN2 (0.51) | L3MBTL1AURKALMNAMEN1KMT2A | |
| SCHEMBL29367625 | 0.85 | LMNA (0.65) | L3MBTL1AURKALMNAMEN1KMT2A | |
| SCHEMBL699273 | 0.85 | LMNA (0.65) | L3MBTL1AURKALMNAMEN1KMT2A | |
| SCHEMBL6840347 | 0.83 | AURKA (0.64) | L3MBTL1NPSR1AURKALMNAMEN1 | |
| SCHEMBL28492436 | 0.82 | SMN1; SMN2 (0.57) | NPSR1LMNAMEN1KMT2ATNKS | |
| SCHEMBL16657405 | 0.80 | TNKS (0.51) | L3MBTL1NPSR1AURKALMNAMEN1 | |
| SCHEMBL16634710 | 0.80 | DAO (0.54) | L3MBTL1NPSR1AURKALMNAMEN1 | |
| SCHEMBL21463671 | 0.79 | DAO (0.50) | L3MBTL1AURKALMNAMEN1KMT2A | |
| SCHEMBL2256170 | 0.79 | SMN1; SMN2 (0.78) | NPSR1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL25698297 | 0.79 | HSD11B1 (0.52) | L3MBTL1AURKALMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015052675-A1 | SUBSTITUTED DIHYDRO-BENZIMIDAZOLE COMPOUNDS AS ROR GAMMA MODULATORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2015-04-16 | — | — | WO | disclosed |