Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | NAAA | Q02083 | 4/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3624207 | 0.98 | NAAA (0.70) | TSHRHTTNAAAHPGDHCRTR1 | |
| SCHEMBL11174324 | 0.98 | NAAA (0.70) | TSHRHTTNAAAHPGDHCRTR1 | |
| SCHEMBL29444016 | 0.95 | TSHR (0.77) | TSHRHTTNAAAHPGDHCRTR1 | |
| SCHEMBL823548 | 0.90 | ALOX5 (0.59) | TSHRHTTNAAAHPGDHCRTR1 | |
| SCHEMBL13869128 | 0.89 | NAAA (0.58) | TSHRHTTNAAAHPGDALDH1A1 | |
| SCHEMBL9260536 | 0.86 | HTT (0.86) | TSHRHTTNAAAHPGDHCRTR1 | |
| SCHEMBL5362359 | 0.86 | HTT (0.86) | TSHRHTTNAAAHPGDHCRTR1 | |
| SCHEMBL11089468 | 0.86 | HTT (0.86) | TSHRHTTNAAAHPGDHCRTR1 | |
| SCHEMBL11078107 | 0.86 | HTT (0.86) | TSHRHTTNAAAHPGDHCRTR1 | |
| SCHEMBL12062401 | 0.85 | TSHR (0.62) | TSHRHTTNAAAHPGDHCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015054337-A1 | HETEROCYCLIC COUPLING CATALYSTS AND METHODS RELATED THERETO | EMORY UNIVERSITY (US) | 2015-04-16 | — | — | WO | disclosed |