Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 9/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29987037 | 1.00 | ALDH1A1 (0.49) | ALDH1A1NPSR1MEN1RECQLKMT2A | |
| SCHEMBL288384 | 1.00 | ALDH1A1 (0.49) | ALDH1A1NPSR1MEN1RECQLKMT2A | |
| SCHEMBL29986539 | 1.00 | ALDH1A1 (0.49) | ALDH1A1NPSR1MEN1RECQLKMT2A | |
| SCHEMBL6440343 | 1.00 | ALDH1A1 (0.49) | ALDH1A1NPSR1MEN1RECQLKMT2A | |
| SCHEMBL1468174 | 1.00 | ALDH1A1 (0.49) | ALDH1A1NPSR1MEN1RECQLKMT2A | |
| SCHEMBL5980144 | 1.00 | ALDH1A1 (0.49) | ALDH1A1NPSR1MEN1RECQLKMT2A | |
| SCHEMBL38558 | 1.00 | ALDH1A1 (0.49) | ALDH1A1NPSR1MEN1RECQLKMT2A | |
| SCHEMBL38557 | 1.00 | ALDH1A1 (0.49) | ALDH1A1NPSR1MEN1RECQLKMT2A | |
| SCHEMBL1468176 | 1.00 | ALDH1A1 (0.49) | ALDH1A1NPSR1MEN1RECQLKMT2A | |
| SCHEMBL6440341 | 1.00 | ALDH1A1 (0.49) | ALDH1A1NPSR1MEN1RECQLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10316080-B2 | Protein-polymer-drug conjugates | ASANA BIOSCIENCES, LLC (US) | 2019-06-11 | — | — | US | disclosed |
| US-20180140716-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | MERSANA THERAPEUTICS, INC. | 2018-05-24 | — | — | US | disclosed |
| EP-3054992-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | Asana BioSciences, LLC (US) | 2016-08-17 | — | — | EP | disclosed |
| US-20150125474-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | MERSANA THERAPEUTICS, INC. | 2015-05-07 | — | — | US | disclosed |
| WO-2015054669-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | ASANA BIOSCIENCES, LLC (US) | 2015-04-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10316080-B2 | Protein-polymer-drug conjugates | PBRM1, STAMBP, TSPO | ALDH1A1 3681/4885NPSR1 3131/4885MEN1 2537/4885 |
| US-20180140716-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | PBRM1, STAMBP, TSPO | ALDH1A1 3681/4885NPSR1 3131/4885MEN1 2537/4885 |
| US-20150125474-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | PBRM1, STAMBP, TSPO | ALDH1A1 3681/4885NPSR1 3131/4885MEN1 2537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.