SCHEMBL166358

SCHEMBL166358

CCC(C)(N=NC(C)(CC)C(=O)O)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.38
ALDH1A1 P00352 2/20 0.38
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36
HIF1A Q16665 1/20 0.36
FFAR3 O14843 1/20 0.33
MEN1 O00255 1/20 0.33
CYP1A2 P05177 1/20 0.33
THRB P10828 1/20 0.33
KMT2A Q03164 1/20 0.33
HMGCR P04035 1/20 0.32
CHRM1 P11229 1/20 0.32
TBXA2R P21731 1/20 0.32
ADRA1A P35348 1/20 0.32
KDM4C Q9H3R0 1/20 0.31
TET2 Q6N021 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL503277 1.00 TSHR (0.38) TSHRALDH1A1CYP2D6CYP2C19HIF1A
SCHEMBL7636275 0.91 TSHR (0.32) TSHRALDH1A1CYP2D6CYP2C19HIF1A
SCHEMBL5142703 0.91 TSHR (0.32) TSHRALDH1A1CYP2D6CYP2C19HIF1A
SCHEMBL8092800 0.87
SCHEMBL4659795 0.87
SCHEMBL15158095 0.85
SCHEMBL15158094 0.85
SCHEMBL30032966 0.80
SCHEMBL5612650 0.79 ALDH1A1 (0.35) TSHRALDH1A1CYP2D6CYP2C19HIF1A
SCHEMBL17938590 0.79 ALDH1A1 (0.35) TSHRALDH1A1CYP2D6CYP2C19HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1676 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120118446-A Heat-resistant acrylic ester-styrene-acrylonitrile core-shell grafted copolymer, latex thereof and preparation method thereof 上海中化科技有限公司 2025-06-10 CN claimed
CN-120118447-A Silicon-containing acrylic ester-styrene-acrylonitrile core-shell graft copolymer, latex thereof and preparation method thereof 上海中化科技有限公司 2025-06-10 CN claimed
US-20240248401-A1 RESIN AND 193 NM DRY PHOTORESIST CONTAINING SAME, AND PREPARATION METHOD THEREFOR AND USE THEREOF CHINA ADVANCED LITHOGRAPHIC MATERIAL TECHNOLOGY CO., LTD. (CN) 2024-07-25 US claimed
CN-118221941-A Silicon-containing acrylic ester-styrene-acrylonitrile core-shell grafted copolymer and preparation method thereof 上海中化科技有限公司 2024-06-21 CN claimed
US-11737957-B2 Dental curable composition including chain transfer agent SHOFU INC. (JP) 2023-08-29 US claimed
US-20230212340-A1 CONTRAST AGENT FOR 3D EX VIVO IMAGING OF VASCULAR AND TUBULAR STRUCTURES IN THE KIDNEY Universität Zürich (CH) 2023-07-06 US claimed
EP-4069316-A1 CONTRAST AGENT FOR 3D EX VIVO IMAGING OF VASCULAR AND TUBULAR STRUCTURES IN THE KIDNEY Universität Zürich (CH) 2022-10-12 EP claimed
WO-2021110991-A1 CONTRAST AGENT FOR 3D EX VIVO IMAGING OF VASCULAR AND TUBULAR STRUCTURES IN THE KIDNEY Universität Zürich (CH) 2021-06-10 WO claimed
US-20180369076-A1 DENTAL CURABLE COMPOSITION INCLUDING CHAIN TRANSFER AGENT SHOFU INC (JP) 2018-12-27 US claimed
EP-2586804-A2 Photoradically and thermally radically curable composition KANEKA CORPORATION (JP) 2013-05-01 EP claimed
US-8084558-B2 Preparation of transition metal nanoparticles and surfaces modified with (co)polymers synthesized by RAFT UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2011-12-27 US claimed
EP-2152830-A1 CORROSION-PREVENTIVE ADHESIVE COMPOSITIONS Henkel AG & Co. KGaA (DE) 2010-02-17 EP claimed
EP-1149075-B1 SYNTHESIS OF DITHIOESTER CHAIN TRANSFER AGENTS COMMW SCIENT IND RES ORG (AU) 2008-12-31 EP claimed
WO-2008147683-A1 CORROSION-PREVENTIVE ADHESIVE COMPOSITIONS HENKEL AG & CO. KGAA (DE) 2008-12-04 WO claimed
US-20080292801-A1 Corrosion-Preventive Adhesive Compositions NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 2008-11-27 US claimed
US-6268452-B1 POLYMERIZATION OF DIALKYLALLYLAMINE WITH POLYMERIZATION OF ADDITION SALT IN SOLVENT AND RADICAL POLYMER POLYMERIZATION WITH AZO COMPOUNDS NITTO BOSEKI CO., LTD. (JP) 2001-07-31 US claimed
US-4533652-A Azo polymerization initiator composition WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1985-08-06 US claimed
US-4208005-A Method for mounting parts on circuit boards HITACHI, LTD. (JP) 1980-06-17 US claimed
US-6391433-B1 None US disclosed
US-3931111-A SOLUBLE HYDROPHILIC POLYMERS AND PROCESS FOR PROCESSING THE SAME CESKOSLOVENSKA AKADAMIE VED (CS) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230212340-A1 CONTRAST AGENT FOR 3D EX VIVO IMAGING OF VASCULAR AND TUBULAR STRUCTURES IN THE KIDNEY REN, FLT4, FLT1 TSHR 2285/4885ALDH1A1 1824/4885CYP2D6 3896/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.