Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.45 |
| ▸ | NPC1 | O15118 | 10/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1663608 | 0.99 | RAB9A (0.45) | RAB9ANPC1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL1664636 | 0.93 | RAB9A (0.45) | RAB9ANPC1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL1664637 | 0.92 | RAB9A (0.45) | RAB9ANPC1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL1664298 | 0.85 | RAB9A (0.50) | RAB9ANPC1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL27918307 | 0.84 | KMT2A (0.48) | RAB9ANPC1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL1666178 | 0.83 | MAPK10 (0.41) | RAB9ANPC1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL1664181 | 0.82 | MAPT (0.50) | RAB9ANPC1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL1665850 | 0.82 | HPGDS (0.50) | RAB9ANPC1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL1664183 | 0.81 | MAPT (0.49) | RAB9ANPC1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL1663527 | 0.81 | MAPK10 (0.40) | RAB9ANPC1MAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2642994-A2 | USE OF HEMATOPOIETIC GROWTH FACTOR MIMETICS | Ligand Pharmaceuticals Incorporated (US) | 2013-10-02 | — | — | EP | disclosed |
| EP-2488486-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | Ligand Pharmaceuticals Inc. (US) | 2012-08-22 | — | — | EP | disclosed |
| WO-2012068406-A2 | USE OF HEMATOPOIETIC GROWTH FACTOR MIMETICS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2012-05-24 | — | — | WO | disclosed |
| WO-2011046954-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2011-04-21 | — | — | WO | disclosed |