Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1D2 | Q14995 | 2/20 | 1.00 |
| ▸ | CCR3 | P51677 | 5/20 | 0.40 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29906522 | 1.00 | NR1D2 (1.00) | NR1D2CCR3NR1D1CACNA1GSSTR3 | |
| Hydrochloric Acid SCHEMBL17982830 | 0.99 | NR1D2 (0.98) | NR1D2CCR3NR1D1CACNA1GSSTR3 | |
| SCHEMBL16636802 | 0.91 | NR1D2 (0.83) | NR1D2NR1D1SSTR3CCNT1 | |
| SCHEMBL29906510 | 0.84 | NR1D2 (0.73) | NR1D2NR1D1SSTR3 | |
| SCHEMBL18021950 | 0.84 | NR1D2 (0.73) | NR1D2NR1D1SSTR3 | |
| SCHEMBL17982824 | 0.83 | NR1D2 (0.71) | NR1D2NR1D1 | |
| Hydrochloric Acid SCHEMBL16638032 | 0.83 | NR1D2 (0.71) | NR1D2NR1D1 | |
| SCHEMBL26556315 | 0.81 | NR1D2 (0.68) | NR1D2NR1D1 | |
| SCHEMBL18021971 | 0.76 | NR1D2 (0.61) | NR1D2NR1D1 | |
| Hydrochloric Acid SCHEMBL17982785 | 0.75 | NR1D2 (0.60) | NR1D2NR1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110709507-A | Natural killer cell | 帝国理工学院 | 2020-01-17 | — | — | CN | claimed |
| US-20230330145-A1 | NATURAL KILLER CELLS | IMPERIAL COLLEGE INNOVATION LIMITED (GB) | 2023-10-19 | — | — | US | disclosed |
| US-20230330145-A1 | NATURAL KILLER CELLS | IMPERIAL COLLEGE INNOVATION LIMITED (GB) | 2023-10-19 | — | — | US | disclosed |
| EP-4137563-A1 | NATURAL KILLER CELLS | Imperial College Innovations Limited (GB) | 2023-02-22 | — | — | EP | disclosed |
| US-11566226-B2 | Natural killer cells | IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) | 2023-01-31 | — | — | US | disclosed |
| US-11559547-B2 | Natural killer cells | IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) | 2023-01-24 | — | — | US | disclosed |
| US-20230002732-A1 | NATURAL KILLER CELLS | IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) | 2023-01-05 | — | — | US | disclosed |
| EP-3601535-A1 | NATURAL KILLER CELLS | Imperial College Of Science, Technology And Medicine (GB) | 2020-02-05 | — | — | EP | disclosed |
| US-20200032210-A1 | NATURAL KILLER CELLS | IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE (GB) | 2020-01-30 | — | — | US | disclosed |
| CN-110709507-A | Natural killer cell | 帝国理工学院 | 2020-01-17 | — | — | CN | disclosed |
| US-9949968-B2 | Diarylalkylamine REV-ERB antagonists and their use as medicaments | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2018-04-24 | — | — | US | disclosed |
| US-9949968-B2 | Diarylalkylamine REV-ERB antagonists and their use as medicaments | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2018-04-24 | — | — | US | disclosed |
| US-20170136009-A1 | DIARYLALKYLAMINE REV-ERB ANTAGONISTS AND THEIR USE AS MEDICAMENTS | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2017-05-18 | — | — | US | disclosed |
| US-20170136009-A1 | DIARYLALKYLAMINE REV-ERB ANTAGONISTS AND THEIR USE AS MEDICAMENTS | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2017-05-18 | — | — | US | disclosed |
| US-9611245-B2 | Diarylalkylamine REV-ERB antagonists and their use as medicaments | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2017-04-04 | — | — | US | disclosed |
| US-9611245-B2 | Diarylalkylamine REV-ERB antagonists and their use as medicaments | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2017-04-04 | — | — | US | disclosed |
| US-20160237057-A1 | DIARYLALKYLAMINE REV-ERB ANTAGONISTS AND THEIR USE AS MEDICAMENTS | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2016-08-18 | — | — | US | disclosed |
| US-20160237057-A1 | DIARYLALKYLAMINE REV-ERB ANTAGONISTS AND THEIR USE AS MEDICAMENTS | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2016-08-18 | — | — | US | disclosed |
| EP-3055293-A1 | DIARYLALKYLAMINE REV-ERB ANTAGONISTS AND THEIR USE AS MEDICAMENTS | Fondazione Istituto Italiano di Tecnologia (IT) | 2016-08-17 | — | — | EP | disclosed |
| WO-2015052283-A1 | DIARYLALKYLAMINE REV-ERB ANTAGONISTS AND THEIR USE AS MEDICAMENTS | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2015-04-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230330145-A1 | NATURAL KILLER CELLS | PBK, NFATC1, IKZF2 | NR1D2 2428/4885CCR3 127/4885NR1D1 1774/4885 |
| US-11559547-B2 | Natural killer cells | PBK, NFATC1, IKZF2 | NR1D2 2428/4885CCR3 127/4885NR1D1 1774/4885 |
| US-20160237057-A1 | DIARYLALKYLAMINE REV-ERB ANTAGONISTS AND THEIR USE AS MEDICAMENTS | NR1D1, NR1I3, BCOR | NR1D2 9/4885CCR3 3793/4885NR1D1 1/4885 |
| US-20200032210-A1 | NATURAL KILLER CELLS | PBK, NFATC1, IKZF2 | NR1D2 2428/4885CCR3 127/4885NR1D1 1774/4885 |
| US-20170136009-A1 | DIARYLALKYLAMINE REV-ERB ANTAGONISTS AND THEIR USE AS MEDICAMENTS | NR1D1, NR1I3, BCOR | NR1D2 9/4885CCR3 3770/4885NR1D1 1/4885 |
| US-11566226-B2 | Natural killer cells | PBK, NFATC1, IKZF2 | NR1D2 2428/4885CCR3 127/4885NR1D1 1774/4885 |
| US-20230002732-A1 | NATURAL KILLER CELLS | PBK, NFATC1, IKZF2 | NR1D2 2428/4885CCR3 127/4885NR1D1 1774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.