Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL2 | P60568 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | STIM1 | Q13586 | 3/20 | 0.33 |
| ▸ | ORAI1 | Q96D31 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16636877 | 0.93 | SMN1; SMN2 (0.38) | IL2MAPTPOLBALOX15MAPK1 | |
| SCHEMBL16636755 | 0.91 | IL2 (0.45) | IL2POLBSTIM1ORAI1ALDH1A1 | |
| SCHEMBL16636870 | 0.84 | IL2 (0.37) | IL2POLBALOX15MAPK1STIM1 | |
| SCHEMBL17997393 | 0.83 | CYP1A2 (0.38) | MAPTALOX15MAPK1ALDH1A1HPGD | |
| SCHEMBL16636669 | 0.81 | POLB (0.41) | IL2MAPTPOLBALOX15STIM1 | |
| SCHEMBL16636656 | 0.79 | IL2 (0.49) | IL2MAPTSTIM1ORAI1ALDH1A1 | |
| SCHEMBL16636856 | 0.78 | MAPT (0.45) | MAPTPOLBALDH1A1HPGDMEN1 | |
| SCHEMBL16636934 | 0.77 | IL2 (0.47) | IL2STIM1ORAI1MEN1KMT2A | |
| SCHEMBL16637637 | 0.76 | KDM4E (0.39) | ALDH1A1MEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL16636716 | 0.75 | IL2 (0.45) | IL2MAPTSTIM1ORAI1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015054283-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA, INC. (US) | 2015-04-16 | — | — | WO | disclosed |