Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16644206 | 0.81 | KDM4E (0.33) | KDM4EKMT2ALMNA | |
| SCHEMBL16636877 | 0.80 | SMN1; SMN2 (0.38) | KDM4EMEN1KMT2ARAB9ALMNA | |
| SCHEMBL16636486 | 0.76 | IL2 (0.37) | KDM4EALDH1A1MEN1KMT2AHTT | |
| SCHEMBL16636755 | 0.74 | IL2 (0.45) | KDM4EALDH1A1MEN1KMT2AHTT | |
| SCHEMBL16636856 | 0.74 | MAPT (0.45) | KDM4EALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL17997393 | 0.71 | CYP1A2 (0.38) | KDM4ECYP1A2ALDH1A1PPARGNCOA2 | |
| SCHEMBL17997392 | 0.69 | KMT2A (0.34) | KDM4EKMT2ALMNA | |
| SCHEMBL16636669 | 0.69 | POLB (0.41) | KDM4EALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL31222089 | 0.68 | L3MBTL1 (0.47) | KDM4EALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL16636716 | 0.67 | IL2 (0.45) | MEN1KMT2ARAB9ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015054283-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA, INC. (US) | 2015-04-16 | — | — | WO | disclosed |