Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16637733 | 0.86 | CTSK (0.51) | CTSK | |
| SCHEMBL16617540 | 0.85 | CTSK (0.41) | CTSKGRM5 | |
| SCHEMBL16617538 | 0.85 | CTSK (0.48) | CTSKGRM5 | |
| SCHEMBL16617687 | 0.82 | GRM5 (0.33) | CTSKGRM5 | |
| SCHEMBL16617688 | 0.82 | GRM5 (0.33) | CTSKGRM5 | |
| SCHEMBL16617283 | 0.75 | CTSK (0.42) | CTSKGRM5 | |
| SCHEMBL16617378 | 0.75 | CTSK (0.48) | CTSKGRM5 | |
| SCHEMBL16617281 | 0.75 | CTSK (0.48) | CTSKGRM5 | |
| SCHEMBL16617379 | 0.75 | CTSK (0.42) | CTSKGRM5 | |
| SCHEMBL16638095 | 0.73 | CTSK (0.35) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3055314-A1 | CATHEPSIN CYSTEINE PROTEASE INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2016-08-17 | — | — | EP | disclosed |
| WO-2015054089-A1 | CATHEPSIN CYSTEINE PROTEASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2015-04-16 | — | — | WO | disclosed |