Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
| ▸ | CETP | P11597 | 2/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.32 |
| ▸ | CDC25A | P30304 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3146702 | 0.71 | PIK3CA (0.42) | TSHRTP53CYP3A4CYP19A1ALOX5 | |
| SCHEMBL13685566 | 0.70 | PTPN1 (0.33) | TSHRPTPN1 | |
| SCHEMBL2247102 | 0.70 | PTPN1 (0.33) | TSHRPTPN1 | |
| SCHEMBL2250831 | 0.70 | PTPN1 (0.33) | TSHRPTPN1 | |
| SCHEMBL12658772 | 0.69 | PTPN2 (0.44) | TSHRCYP3A4MAPKAPK2PTPN1PTPN2 | |
| SCHEMBL14722991 | 0.69 | PTPN2 (0.44) | TSHRCYP3A4MAPKAPK2PTPN1PTPN2 | |
| SCHEMBL15945065 | 0.69 | PTPN2 (0.44) | TSHRCYP3A4MAPKAPK2PTPN1PTPN2 | |
| SCHEMBL2250976 | 0.68 | PTPN1 (0.35) | PTPN1 | |
| SCHEMBL2248568 | 0.68 | PTPN1 (0.35) | PTPN1 | |
| SCHEMBL2246264 | 0.68 | PTPN1 (0.35) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015134467-A1 | METHODS AND COMPOSITIONS FOR DIRECT RADIOACTIVE LABELING OF BIO-ACTIVE MOLECULES AND BUILDING BLOCKS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2015-09-11 | — | — | WO | claimed |
| WO-2015054476-A1 | C-HALOGEN BOND FORMATION | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2015-04-16 | — | — | WO | disclosed |