Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 4/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.42 |
| ▸ | CETP | P11597 | 3/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17394853 | 0.78 | PIK3CA (0.42) | PIK3CAPIK3CGCETPCYP19A1PTGS2 | |
| SCHEMBL17394844 | 0.78 | PIK3CA (0.42) | PIK3CAPIK3CGCETPCYP19A1PTGS2 | |
| SCHEMBL21917264 | 0.73 | CYP19A1 (0.49) | CETPCYP19A1ALOX5ALOX15ALOX12 | |
| SCHEMBL14880005 | 0.73 | CYP19A1 (0.49) | CETPCYP19A1ALOX5ALOX15ALOX12 | |
| SCHEMBL266913 | 0.72 | CYP19A1 (0.44) | CETPCYP19A1ALOX5ALOX15ALOX12 | |
| SCHEMBL9418499 | 0.72 | CYP19A1 (0.40) | CYP19A1TSHRKDM4EMEN1KMT2A | |
| SCHEMBL9418494 | 0.72 | CYP19A1 (0.40) | CYP19A1TSHRKDM4EMEN1KMT2A | |
| SCHEMBL3146912 | 0.72 | CYP19A1 (0.44) | CETPCYP19A1ALOX5ALOX15ALOX12 | |
| SCHEMBL3536691 | 0.71 | CA1 (0.38) | PIK3CAPIK3CGCETPCYP19A1PTGS2 | |
| SCHEMBL16637469 | 0.71 | TSHR (0.36) | PIK3CAPIK3CGCETPCYP19A1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101223123-B | Naphthalenone derivative with powdery-ionone type odours | FIRMENICH S.A. (CH) | 2011-11-30 | — | — | CN | disclosed |
| EP-1910262-B1 | NAPHTHALENONE DERIVATIVE WITH POWDERY-IONONE TYPE ODOURS | FIRMENICH & CIE (CH) | 2010-03-03 | — | — | EP | disclosed |
| US-20080214419-A1 | Naphthalenone Derivative with Powdery-Ionone Type Odors | FIRMENICH SA (CH) | 2008-09-04 | — | — | US | disclosed |
| CN-101223123-A | Naphthalenone derivative with powdery-ionone type odours | FIRMENICH & CIE (CH) | 2008-07-16 | — | — | CN | disclosed |
| EP-1910262-A1 | NAPHTHALENONE DERIVATIVE WITH POWDERY-IONONE TYPE ODOURS | FIRMENICH SA (CH) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007010420-A1 | NAPHTHALENONE DERIVATIVE WITH POWDERY-IONONE TYPE ODOURS | FIRMENICH SA (CH) | 2007-01-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080214419-A1 | Naphthalenone Derivative with Powdery-Ionone Type Odors | IPO5, TRPA1, SCN5A | PIK3CA 3046/4885PIK3CG 2930/4885CETP 1614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.