SCHEMBL16637590

SCHEMBL16637590

CC(O)(O)C(O)(O)CCc1cnccn1

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
CYP1A2 P05177 1/20 0.33
XDH P47989 1/20 0.32
TXNRD1 Q16881 1/20 0.32
HRH1 P35367 1/20 0.32
KDM4E B2RXH2 2/20 0.32
POLB P06746 1/20 0.32
ALDH1A1 P00352 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
VNN1 O95497 1/20 0.31
CYP19A1 P11511 1/20 0.30
DAO P14920 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15170636 0.82 POLB (0.35) HDAC3HDAC1HDAC2HDAC6POLB
SCHEMBL9751446 0.81 NUDT1 (0.37) HDAC3HDAC1HDAC2HDAC6CYP1A2
SCHEMBL21025398 0.76 BRS3 (0.37) HDAC3HDAC1HDAC2HDAC6CYP1A2
SCHEMBL8125836 0.74 HDAC3 (0.34) HDAC3HDAC1HDAC2HDAC6CYP1A2
SCHEMBL14003761 0.73 HRH3 (0.36) HDAC3HDAC1HDAC2HDAC6CYP1A2
SCHEMBL27967981 0.71 ADORA3 (0.38) HDAC3HDAC1HDAC2HDAC6CYP1A2
SCHEMBL21740803 0.70 KDM4E (0.41) HDAC3HDAC1HDAC2HDAC6XDH
SCHEMBL29530008 0.70
SCHEMBL30390174 0.70
SCHEMBL839885 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015054452-A1 KERATIN CONDITIONING BIO-BASED POLYMERS FOR USE IN PERSONAL CARE COMPOSITIONS BASF SE (DE) 2015-04-16 WO disclosed