Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.59 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.46 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.46 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.45 |
| ▸ | TLR2 | O60603 | 3/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.43 |
| ▸ | RRM1 | P23921 | 1/20 | 0.43 |
| ▸ | EPOR | P19235 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18551937 | 0.95 | GLP1R (0.64) | GLP1RGNAI3GNAO1GNAI1DPP7 | |
| SCHEMBL17922789 | 0.92 | GLP1R (0.54) | GLP1RGNAI3GNAO1GNAI1DPP7 | |
| SCHEMBL17922791 | 0.91 | GLP1R (0.60) | GLP1RGNAI3GNAO1GNAI1DPP7 | |
| SCHEMBL16493177 | 0.91 | GLP1R (0.53) | GLP1RGNAI3GNAO1GNAI1DPP7 | |
| SCHEMBL20146951 | 0.90 | GLP1R (0.52) | GLP1RGNAI3GNAO1GNAI1DPP7 | |
| SCHEMBL16947980 | 0.87 | GLP1R (0.53) | GLP1RTLR2EPHX2NOD1EPOR | |
| SCHEMBL19049678 | 0.87 | GLP1R (0.55) | GLP1REPHX2NOD1EPOR | |
| SCHEMBL19034958 | 0.87 | GLP1R (0.55) | GLP1REPHX2NOD1EPOR | |
| SCHEMBL19034928 | 0.87 | GLP1R (0.55) | GLP1REPHX2NOD1EPOR | |
| SCHEMBL19034938 | 0.87 | GLP1R (0.55) | GLP1REPHX2NOD1EPOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9006178-B2 | Double-acylated GLP-1 derivatives with a linker | NOVO NORDISK A/S (DK) | 2015-04-14 | — | — | US | disclosed |