Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.52 |
| ▸ | EPOR | P19235 | 4/20 | 0.41 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | RRM1 | P23921 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
| ▸ | CD40 | P25942 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18560331 | 0.95 | GLP1R (0.50) | GLP1REPORTLR2NOD1 | |
| SCHEMBL24415179 | 0.92 | GLP1R (0.47) | GLP1REPORNOD1 | |
| SCHEMBL17922789 | 0.92 | GLP1R (0.54) | GLP1REPORGNAI3GNAO1GNAI1 | |
| SCHEMBL16493177 | 0.91 | GLP1R (0.53) | GLP1REPORGNAI3GNAO1GNAI1 | |
| SCHEMBL20652812 | 0.90 | GLP1R (0.49) | GLP1REPORGNAI3GNAO1GNAI1 | |
| SCHEMBL16638308 | 0.90 | GLP1R (0.59) | GLP1REPORGNAI3GNAO1GNAI1 | |
| SCHEMBL18551937 | 0.89 | GLP1R (0.64) | GLP1RGNAI3GNAO1GNAI1TLR2 | |
| SCHEMBL27274276 | 0.88 | RRM1 (0.50) | GLP1REPORGNAI3GNAO1GNAI1 | |
| SCHEMBL24538414 | 0.87 | GLP1R (0.65) | GLP1RNOD1 | |
| SCHEMBL23253773 | 0.87 | GLP1R (0.65) | GLP1RNOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2637699-B1 | DOUBLE-ACYLATED GLP-1 DERIVATIVES WITH A LINKER | NOVO NORDISK AS (DK) | 2018-05-16 | — | — | EP | disclosed |