SCHEMBL16638376

SCHEMBL16638376

C=C(C)C(=O)Oc1ccc(S(=O)(=O)NS(=O)(=O)CF)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 3/20 0.44
KMT2A Q03164 2/20 0.42
ATM Q13315 1/20 0.42
POLB P06746 2/20 0.41
PKM P14618 2/20 0.41
MAPT P10636 1/20 0.41
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
MMP1 P03956 2/20 0.36
MMP2 P08253 2/20 0.36
MMP9 P14780 2/20 0.36
MMP13 P45452 2/20 0.36
MMP8 P22894 1/20 0.36
TSHR P16473 1/20 0.36
PRTN3 P24158 1/20 0.36
CA12 O43570 1/20 0.35
CA9 Q16790 1/20 0.35
EGFR P00533 1/20 0.35
ERBB2 P04626 1/20 0.35
SMN1; SMN2 Q16637 4/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14268209 0.84 KMT2A (0.48) ELANEKMT2AATMPOLBPKM
SCHEMBL7784467 0.83 ELANE (0.47) ELANEKMT2AATMPOLBPKM
SCHEMBL7784371 0.83 MMP2 (0.53) ELANEKMT2AATMPKMMAPT
SCHEMBL2742199 0.82 ELANE (0.43) ELANEKMT2AATMPOLBPKM
SCHEMBL3250093 0.81 SMN1; SMN2 (0.56) ELANEKMT2AATMPOLBPKM
SCHEMBL3246096 0.80 ELANE (0.47) ELANEKMT2AATMPOLBPKM
SCHEMBL3248031 0.80 ALDH1A1 (0.50) ELANEKMT2AATMPOLBPKM
SCHEMBL14268204 0.80 SMN1; SMN2 (0.54) ELANEKMT2AATMPOLBPKM
SCHEMBL14268210 0.80 ELANE (0.43) ELANEKMT2AATMPOLBPKM
SCHEMBL3242479 0.78 ALDH1A1 (0.58) ELANEKMT2APOLBPKMMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9005870-B2 Actinic-ray- or radiation-sensitive resin composition and method of forming pattern using the composition FUJIFILM CORPORATION (JP) 2015-04-14 US disclosed