Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CA3 | P07451 | 2/20 | 0.35 |
| ▸ | CA5A | P35218 | 2/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | THPO | P40225 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1806852 | 0.97 | MAOA (0.37) | MAOAMAOBLMNATDP1ALOX15 | |
| SCHEMBL16638627 | 0.89 | CA12 (0.55) | MAOAMAOBLMNATDP1ALOX15 | |
| SCHEMBL10064409 | 0.89 | CA12 (0.55) | MAOAMAOBLMNATDP1ALOX15 | |
| SCHEMBL3988309 | 0.87 | PAOX (0.32) | MAOAMAOBPAOX | |
| SCHEMBL11229173 | 0.86 | — | — | |
| SCHEMBL3134640 | 0.86 | — | — | |
| SCHEMBL3315081 | 0.84 | — | — | |
| SCHEMBL9188930 | 0.84 | — | — | |
| SCHEMBL13968030 | 0.84 | PAOX (0.47) | MAOAMAOBLMNATDP1ALOX15 | |
| Hydrochloric Acid SCHEMBL28343626 | 0.84 | MAOA (0.31) | MAOAMAOBLMNATDP1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024209011-A1 | NANOPARTICLE COMPOSITIONS COMPRISING ONE OR MORE VARIANTS OF POLY(D,L-LACTIC- CO-GLYCOLIC ACID) | Københavns Universitet (DK) | 2024-10-10 | — | — | WO | disclosed |
| EP-4225268-A1 | IMPROVED PROCESS AND FORMULATION OF LIPID NANOPARTICLES | Translate Bio, Inc. (US) | 2023-08-16 | — | — | EP | disclosed |
| WO-2022076562-A1 | IMPROVED PROCESS AND FORMULATION OF LIPID NANOPARTICLES | TRANSLATE BIO, INC. (US) | 2022-04-14 | — | — | WO | disclosed |
| US-20160009657-A1 | AMINE-CONTAINING LIPIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-01-14 | — | — | US | disclosed |
| US-9006487-B2 | Amine-containing lipids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160009657-A1 | AMINE-CONTAINING LIPIDS AND USES THEREOF | PHOSPHO1, CHMP4B, SGMS1 | MAOA 643/4885MAOB 410/4885LMNA 402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.