⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28343626 | 0.97 | MAOA (0.31) | — | |
| SCHEMBL1806852 | 0.89 | MAOA (0.37) | — | |
| SCHEMBL8953972 | 0.87 | MAOA (0.40) | — | |
| SCHEMBL16638631 | 0.86 | MAOA (0.36) | — | |
| Diethanolamine SCHEMBL27879356 | 0.83 | ALDH1A1 (0.35) | — | |
| SCHEMBL11367620 | 0.83 | PAOX (0.48) | — | |
| Diethanolamine SCHEMBL8571462 | 0.83 | ALDH1A1 (0.40) | — | |
| Diethanolamine SCHEMBL28705331 | 0.82 | NAAA (0.49) | — | |
| Diethanolamine SCHEMBL28569608 | 0.81 | PAOX (0.38) | — | |
| SCHEMBL9134028 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111643496-A | Methods of using MEK inhibitors | 埃克塞利希斯股份有限公司 | 2020-09-11 | — | — | CN | claimed |
| CN-109575220-A | It is a kind of to spring back aqueous polyurethaneurea elastomer and preparation method thereof fastly | 天津大学 | 2019-04-05 | — | — | CN | claimed |
| CN-109575767-A | A kind of aqueous polyurethaneurea track material and preparation method thereof | 天津大学 | 2019-04-05 | — | — | CN | claimed |
| US-20170166523-A9 | MEK Inhibitors And Methods Of Their Use | EXELIXIS, INC. | 2017-06-15 | — | — | US | claimed |
| US-20150141399-A1 | MEK Inhibitors And Methods Of Their Use | EXELIXIS INC (US) | 2015-05-21 | — | — | US | claimed |
| WO-2009019135-A1 | FLUORESCENT WHITENING NANOPARTICLES | BASF SE (CH) | 2009-02-12 | — | — | WO | claimed |
| US-20080135805-A1 | Fluorescent Pigments for Coating Compositions | CIBA SPECIALTY CHEMICALS CORP. | 2008-06-12 | — | — | US | claimed |
| EP-1778917-A1 | FLUORESCENT PIGMENTS FOR COATING COMPOSITIONS | Ciba SC Holding AG (CH) | 2007-05-02 | — | — | EP | claimed |
| WO-2006015963-A1 | FLUORESCENT PIGMENTS FOR COATING COMPOSITIONS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2006-02-16 | — | — | WO | claimed |
| US-20240383915-A1 | OXAZEPINE COMPOUNDS AND USES THEREOF IN THE TREATMENT OF CANCER | GENENTECH, INC. (US) | 2024-11-21 | — | — | US | disclosed |
| EP-4320132-A1 | OXAZEPINE COMPOUNDS AND USES THEREOF IN THE TREATMENT OF CANCER | Genentech, Inc. (US) | 2024-02-14 | — | — | EP | disclosed |
| CN-117083279-A | Oxazepine compounds and their use in the treatment of cancer | 基因泰克公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-116199588-A | Method for preparing N- (2-hydroxyethyl) -1, 3-propanediamine in semi-continuous mode by combining Y-type micro-mixing reactor and high-pressure reaction kettle | 大连理工大学 | 2023-06-02 | — | — | CN | disclosed |
| WO-2022216762-A1 | OXAZEPINE COMPOUNDS AND USES THEREOF IN THE TREATMENT OF CANCER | GENENTECH, INC. (US) | 2022-10-13 | — | — | WO | disclosed |
| WO-2003022924-A1 | POLYMER DISPERSIONS COMPRISING VINYLAMIDE COPOLYMERS | BASF AKTIENGESELLSCHAFT (DE) | 2003-03-20 | — | — | WO | disclosed |
| WO-2003021041-A2 | METHOD FOR INCREASING THE WHITENESS OF PAPER BY MEANS OF CATIONIC POLYELECTROLYTES | BASF AKTIENGESELLSCHAFT (DE) | 2003-03-13 | — | — | WO | disclosed |
| WO-2003020808-A1 | REINFORCEMENT OF THE EFFECT OF OPTICAL BRIGHTENERS BY MEANS OF POLYMERS | BASF AKTIENGESELLSCHAFT (DE) | 2003-03-13 | — | — | WO | disclosed |
| WO-2003016624-A1 | METHOD FOR PRODUCTION OF COATED PAPER WITH EXTREME WHITENESS | BASF AKTIENGESELLSCHAFT (DE) | 2003-02-27 | — | — | WO | disclosed |
| US-4252604-A | OPTICAL BRIGHTENERS | SANDOZ LTD. (CH) | 1981-02-24 | — | — | US | disclosed |
| US-3947374-A | Substituted halotriazines as peroxygen bleach activators | AMERICAN CYANAMID COMPANY (US) | 1976-03-30 | — | — | US | disclosed |