Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | CA12 | O43570 | 4/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6975222 | 0.98 | TSHR (0.55) | TSHRCA12CA14CA7CA9 | |
| Hydrochloric Acid SCHEMBL5595769 | 0.95 | TSHR (0.52) | TSHRCA12CA14CA7CA9 | |
| SCHEMBL12847508 | 0.91 | TSHR (0.63) | TSHRCA12CA14CA7CA9 | |
| SCHEMBL10042464 | 0.91 | TSHR (0.63) | TSHRCA12CA14CA7CA9 | |
| SCHEMBL72889 | 0.88 | TSHR (0.67) | TSHRCA12CA14CA7CA9 | |
| SCHEMBL5001750 | 0.84 | CA12 (0.61) | TSHRCA12CA14CA7CA9 | |
| SCHEMBL16638640 | 0.83 | MEN1 (0.44) | TSHRCA12CA14CA7CA9 | |
| Hydrochloric Acid SCHEMBL5595818 | 0.83 | CA12 (0.59) | TSHRCA12CA14CA7CA9 | |
| SCHEMBL3633804 | 0.83 | CA12 (0.61) | TSHRCA12CA14CA7CA9 | |
| SCHEMBL12847703 | 0.82 | TSHR (0.52) | TSHRCA12CA14CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9006487-B2 | Amine-containing lipids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-04-14 | — | — | US | disclosed |