SCHEMBL72889

SCHEMBL72889

COC(=O)CCNCCC(=O)OC

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.67
CA12 O43570 5/20 0.58
CA14 Q9ULX7 5/20 0.58
KMT2A Q03164 2/20 0.48
MEN1 O00255 1/20 0.48
LMNA P02545 3/20 0.46
KDM4E B2RXH2 1/20 0.46
LTA4H P09960 1/20 0.46
HSD17B10 Q99714 2/20 0.46
MGAM O43451 1/20 0.46
GAA P10253 1/20 0.46
SI P14410 1/20 0.46
MGAM2 Q2M2H8 1/20 0.46
CA7 P43166 3/20 0.45
CA9 Q16790 3/20 0.45
ALDH1A1 P00352 2/20 0.44
MAPT P10636 1/20 0.44
HTT P42858 1/20 0.44
CA2 P00918 1/20 0.44
EPHX2 P34913 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12847508 0.97 TSHR (0.63) TSHRCA12CA14KMT2AMEN1
SCHEMBL10042464 0.97 TSHR (0.63) TSHRCA12CA14KMT2AMEN1
SCHEMBL29915714 0.92 TSHR (0.59) TSHRCA12CA14KMT2AMEN1
SCHEMBL12791500 0.92 TSHR (0.59) TSHRCA12CA14KMT2AMEN1
SCHEMBL23085540 0.90 TSHR (0.64) TSHRCA12CA14KMT2AMEN1
SCHEMBL11193382 0.90 TSHR (0.60) TSHRCA12CA14KMT2AMEN1
SCHEMBL5701454 0.90 TSHR (0.55) TSHRCA12CA14KMT2AMEN1
SCHEMBL6975222 0.90 TSHR (0.55) TSHRCA12CA14KMT2AMEN1
SCHEMBL12847481 0.88 TSHR (0.52) TSHRCA12CA14KMT2AMEN1
SCHEMBL12847703 0.88 TSHR (0.52) TSHRCA12CA14KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3431480-B1 DIARYLAMINE-BASED FLUOROGENIC PROBES FOR DETECTION OF PEROXYNITRITE UNIV HONG KONG (CN) 2024-07-03 EP disclosed
EP-3263626-B1 SILICONE SKELETON-CONTAINING POLYMER, PHOTO-CURABLE RESIN COMPOSITION, PHOTO-CURABLE DRY FILM, LAMINATE, AND PATTERNING PROCESS SHINETSU CHEMICAL CO (JP) 2024-03-13 EP disclosed
US-11256174-B2 Pattern forming process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-02-22 US disclosed
EP-3235803-B1 TETRACARBOXYLIC ACID DIESTER COMPOUND, POLYIMIDE PRECURSOR POLYMER AND METHOD FOR PRODUCING THE SAME, NEGATIVE PHOTOSENSITIVE RESIN COMPOSITION, POSITIVE PHOTOSENSITIVE RESIN COMPOSITION, PATTERNING PROCESS, AND METHOD FOR FORMING CURED FILM SHINETSU CHEMICAL CO (JP) 2020-06-03 EP disclosed
US-10654032-B2 Recyclable catalysts for chlorination of organic acids and alcohols GALAXY SURFACTANTS LTD. (IN) 2020-05-19 US disclosed
US-10457779-B2 Tetracarboxylic acid diester compound, polyimide precursor polymer and method for producing the same, negative photosensitive resin composition, positive photosensitive resin composition, patterning process, and method for forming cured film SHIN-ETSU CHEMICAL CO., LTD. (JP) 2019-10-29 US disclosed
US-10451970-B2 Silicone skeleton-containing polymer, photo-curable resin composition, photo-curable dry film, laminate, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2019-10-22 US disclosed
EP-3103831-B1 PHOTO-CURABLE RESIN COMPOSITION AND PHOTO-CURABLE DRY FILM USING THE SAME SHINETSU CHEMICAL CO (JP) 2019-09-04 EP disclosed
CN-110016136-A Novel tetracarboxylic dianhydride, polyimide resin and its manufacturing method, photosensitive resin composition, pattern forming method 信越化学工业株式会社 2019-07-16 CN disclosed
EP-3275857-B1 TETRACARBOXYLIC ACID DIESTER COMPOUND, POLYIMIDE PRECURSOR POLYMER AND METHOD FOR PRODUCING THE SAME, NEGATIVE PHOTOSENSITIVE RESIN COMPOSITION, PATTERNING PROCESS, AND METHOD FOR FORMING CURED FILM SHINETSU CHEMICAL CO (JP) 2019-06-05 EP disclosed
US-20070196454-A1 Crosslinked gels comprising polyalkyleneimines, and their uses as medical devices HYPERBRANCH MEDICAL TECHNOLOGY, INC. (US) 2007-08-23 US disclosed
US-7157594-B2 6-Fluorobicyclo[3.1.0]hexane derivatives TAISHO PHARMACEUTICAL CO., LTD. (JP) 2007-01-02 US disclosed
US-20050119345-A1 6-Fluorobicyclo[3.1.0]hexane derivatives TAISHO PHARMACEUTICAL CO., LTD. (JP) 2005-06-02 US disclosed
EP-1459765-A1 6-FLUOROBICYCLO 3.1.0 HEXANE DERIVATIVES TAISHO PHARMACEUTICAL CO., LTD (JP) 2004-09-22 EP disclosed
US-5578633-A VASOPRESSIN AND OXYTOCIN ANTAGONISTS SANOFI (FR) 1996-11-26 US disclosed
US-5481005-A N-sulfonylindoline derivatives, their preparation and the pharmaceutical compositions in which they are present SANOFI (FR) 1996-01-02 US disclosed
US-5397801-A Affinity for vasopressin and ocytocin receptors; disorders of nervous, cardiovascular and gastrointestinal systems SANOFI (FR) 1995-03-14 US disclosed
US-5338755-A Have affinity for vasopressin and ocytocin receptors; intermediates for drugs that act on central nervous system ELF SANOFI (FR) 1994-08-16 US disclosed
US-4772546-A THIADIAZOLE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1988-09-20 US disclosed
US-4587353-A Process for producing N-chlorosulfenyl compounds CIBA-GEIGY CORPORATION (US) 1986-05-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10654032-B2 Recyclable catalysts for chlorination of organic acids and alcohols ADH1C, ADH1A, OTC TSHR 717/4885CA12 778/4885CA14 342/4885
US-20050119345-A1 6-Fluorobicyclo[3.1.0]hexane derivatives GRM1, GRM2, GRM6 TSHR 493/4885CA12 3858/4885CA14 4447/4885
US-10457779-B2 Tetracarboxylic acid diester compound, polyimide precursor polymer and method for producing the same, negative photosensitive resin composition, positive photosensitive resin composition, patterning process, and method for forming cured film ARCN1, COL1A1, F12 TSHR 4289/4885CA12 550/4885CA14 1108/4885
US-20070196454-A1 Crosslinked gels comprising polyalkyleneimines, and their uses as medical devices PLOD3, PLOD2, PLOD1 TSHR 4792/4885CA12 2835/4885CA14 2114/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.