Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | EYA2 | O00167 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16638620 | 1.00 | ALOX15 (0.41) | ALOX15KDM4EMAPTSMN1; SMN2EYA2 | |
| SCHEMBL3109742 | 0.97 | ALOX15 (0.38) | ALOX15KDM4EMAPTSMN1; SMN2TDP1 | |
| SCHEMBL20998889 | 0.89 | TDP1 (0.36) | ALOX15KDM4EEYA2APPACE | |
| SCHEMBL808456 | 0.89 | TDP1 (0.36) | ALOX15KDM4EEYA2APPACE | |
| SCHEMBL899927 | 0.87 | TDP1 (0.37) | ALOX15KDM4EEYA2APPACE | |
| SCHEMBL3319762 | 0.84 | CYP1A2 (0.44) | ALOX15KDM4EMAPTSMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL9711107 | 0.84 | ALOX15 (0.35) | ALOX15KDM4EEYA2APPACE | |
| Ammonia Solution, Strong SCHEMBL10870270 | 0.84 | ALOX15 (0.35) | ALOX15KDM4EEYA2APPACE | |
| SCHEMBL16638621 | 0.82 | PAOX (0.31) | — | |
| Trolamine SCHEMBL14990729 | 0.81 | KDM4E (0.44) | ALOX15KDM4EMAPTSMN1; SMN2EYA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160009657-A1 | AMINE-CONTAINING LIPIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-01-14 | — | — | US | disclosed |
| US-9006487-B2 | Amine-containing lipids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160009657-A1 | AMINE-CONTAINING LIPIDS AND USES THEREOF | PHOSPHO1, CHMP4B, SGMS1 | ALOX15 499/4885KDM4E 2172/4885MAPT 1879/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.