SCHEMBL808456

SCHEMBL808456

NC(=O)CCN(CCC(N)=O)CCN(CCC(N)=O)CCN(CCC(N)=O)CCC(N)=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.36
EYA2 O00167 1/20 0.36
APP P05067 1/20 0.36
ACE P12821 1/20 0.36
ALOX15 P16050 3/20 0.35
BLM P54132 3/20 0.35
PMP22 Q01453 3/20 0.35
CYP2C19 P33261 3/20 0.35
KDM4E B2RXH2 2/20 0.35
LMNA P02545 2/20 0.35
TP53 P04637 2/20 0.35
CYP1A2 P05177 2/20 0.35
CYP3A4 P08684 2/20 0.35
GMNN O75496 1/20 0.35
USP2 O75604 1/20 0.35
ALDH1A1 P00352 1/20 0.35
GLA P06280 1/20 0.35
POLB P06746 1/20 0.35
CYP2C9 P11712 1/20 0.35
HPGD P15428 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20998889 1.00 TDP1 (0.36) TDP1EYA2APPACEALOX15
SCHEMBL899927 0.97 TDP1 (0.37) TDP1EYA2APPACEALOX15
Hydrochloric Acid SCHEMBL9711107 0.94 ALOX15 (0.35) TDP1EYA2APPACEALOX15
Ammonia Solution, Strong SCHEMBL10870270 0.94 ALOX15 (0.35) TDP1EYA2APPACEALOX15
SCHEMBL16638646 0.89 ALOX15 (0.41) TDP1EYA2APPACEALOX15
SCHEMBL16638615 0.89 LCK (0.32) TDP1EYA2APPACEALOX15
SCHEMBL16638620 0.89 ALOX15 (0.41) TDP1EYA2APPACEALOX15
SCHEMBL3109742 0.86 ALOX15 (0.38) TDP1ALOX15BLMPMP22CYP2C19
SCHEMBL10017445 0.86 LCK (0.33) TDP1ALOX15BLMPMP22CYP2C19
SCHEMBL11503750 0.86 LMNA (0.40) TDP1EYA2APPACEALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7897013-B2 Blends of glyoxalated polyacrylamides and paper strengthening agents GEORGIA-PACIFIC CHEMICALS LLC (US) 2011-03-01 US disclosed
US-7897013-B2 Blends of glyoxalated polyacrylamides and paper strengthening agents GEORGIA-PACIFIC CHEMICALS LLC (US) 2011-03-01 US disclosed
US-7863395-B2 Polyacrylamide-based strengthening agent GEORGIA-PACIFIC CHEMICALS LLC (US) 2011-01-04 US disclosed
US-7863395-B2 Polyacrylamide-based strengthening agent GEORGIA-PACIFIC CHEMICALS LLC (US) 2011-01-04 US disclosed
WO-2010059946-A1 BLENDS OF GLYOXALATED POLYACRYLAMIDES AND PAPER STRENGTHENING AGENTS GEORGIA-PACIFIC CHEMICALS LLC (US) 2010-05-27 WO disclosed
US-20090165978-A1 BLENDS OF GLYOXALATED POLYACRYLAMIDES AND PAPER STRENGTHENING AGENTS GEORGIA-PACIFIC CHEMICALS LLC (US) 2009-07-02 US disclosed
US-20090165978-A1 BLENDS OF GLYOXALATED POLYACRYLAMIDES AND PAPER STRENGTHENING AGENTS GEORGIA-PACIFIC CHEMICALS LLC (US) 2009-07-02 US disclosed
WO-2008079531-A2 POLYACRYLAMIDE-BASED STRENGTHENING AGENT GEORGIA-PACIFIC CHEMICALS LLC (US) 2008-07-03 WO disclosed
US-20080149287-A1 POLYACRYLAMIDE-BASED STRENGTHENING AGENT GEORGIA-PACIFIC CHEMICALS LLC (US) 2008-06-26 US disclosed
US-20080149287-A1 POLYACRYLAMIDE-BASED STRENGTHENING AGENT GEORGIA-PACIFIC CHEMICALS LLC (US) 2008-06-26 US disclosed