Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 8/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.53 |
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.49 |
| ▸ | TOP1 | P11387 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15635904 | 0.90 | RAB9A (0.65) | GRM4MEN1KMT2AMAPTRAB9A | |
| SCHEMBL15635675 | 0.90 | GRM4 (0.57) | GRM4MEN1KMT2AMAPTGAA | |
| SCHEMBL16616664 | 0.89 | LMNA (0.58) | MEN1KMT2AMAPTGAARAB9A | |
| SCHEMBL16616153 | 0.86 | MEN1 (0.62) | GRM4MEN1KMT2AMAPTGAA | |
| SCHEMBL16616492 | 0.81 | SMN1; SMN2 (0.55) | MEN1KMT2AMAPTGAARAB9A | |
| SCHEMBL15636196 | 0.81 | GRM4 (0.49) | GRM4MEN1KMT2AMAPTGAA | |
| SCHEMBL10933629 | 0.81 | NPC1 (0.61) | GRM4MEN1KMT2AMAPTRAB9A | |
| SCHEMBL15636615 | 0.81 | GRM4 (0.57) | GRM4MEN1KMT2AMAPTGAA | |
| SCHEMBL15636396 | 0.81 | RAB9A (0.65) | GRM4MEN1KMT2AMAPTRAB9A | |
| SCHEMBL16616459 | 0.79 | MEN1 (0.80) | MEN1KMT2AMAPTGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9006451-B1 | 2-anilinonicotinyl based chalcones useful as potential anticancer agents and process for preparation thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2015-04-14 | — | — | US | disclosed |