Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22924919 | 0.79 | AKT1 (0.47) | CES2CES1ALDH1A1NPC1RAB9A | |
| SCHEMBL17266589 | 0.77 | CES2 (0.43) | CES2CES1PTPN1ERCC5FEN1 | |
| SCHEMBL16502018 | 0.76 | CES2 (0.41) | CES2CES1PTPN1ERCC5FEN1 | |
| SCHEMBL24230171 | 0.73 | HCAR2 (0.34) | PTPN1ERCC5FEN1NPC1RAB9A | |
| SCHEMBL15705122 | 0.73 | CES2 (0.48) | CES2CES1PTPN1ERCC5FEN1 | |
| SCHEMBL18554814 | 0.72 | ALDH1A1 (0.53) | CES2CES1PTPN1ERCC5FEN1 | |
| SCHEMBL149580 | 0.72 | ALDH1A1 (0.53) | CES2CES1PTPN1ERCC5FEN1 | |
| Propene SCHEMBL28028230 | 0.70 | CES2 (0.54) | CES2CES1PTPN1ERCC5FEN1 | |
| SCHEMBL30634467 | 0.69 | CES2 (0.58) | CES2CES1PTPN1ERCC5FEN1 | |
| SCHEMBL118109 | 0.69 | CES2 (0.58) | CES2CES1PTPN1ERCC5FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2161273-B1 | Imidazo[4,5-c]pyridine compounds and methods of antiviral treatment | LEUVEN K U RES & DEV (BE) | 2015-04-15 | — | — | EP | disclosed |