Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 2/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 3/20 | 0.34 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 3/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30990234 | 0.82 | SYK (0.34) | SYKUSP30BACE1BACE2PDPK1 | |
| SCHEMBL1180650 | 0.82 | SYK (0.36) | SYKUSP30BACE1PDPK1SSTR4 | |
| SCHEMBL25385687 | 0.81 | SYK (0.34) | SYKUSP30BACE1BACE2PDPK1 | |
| SCHEMBL30990299 | 0.81 | SSTR4 (0.39) | SYKUSP30BACE1BACE2PDPK1 | |
| SCHEMBL6059048 | 0.80 | SYK (0.37) | SYKUSP30PDPK1SSTR4GRIN2B | |
| SCHEMBL24030998 | 0.79 | USP30 (0.37) | SYKUSP30BACE1PDPK1SSTR4 | |
| SCHEMBL6058650 | 0.79 | SYK (0.37) | SYKUSP30PDPK1SSTR4AAK1 | |
| SCHEMBL3956395 | 0.78 | MAPT (0.38) | SYKUSP30 | |
| SCHEMBL30990198 | 0.76 | SYK (0.35) | SYKBACE1BACE2PDPK1SSTR4 | |
| SCHEMBL16418854 | 0.76 | SYK (0.39) | SYKUSP30BACE1PDPK1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2626350-B1 | CYCLOPROPANE COMPOUND | EISAI R&D MAN CO LTD (JP) | 2015-04-15 | — | — | EP | disclosed |