Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1180650 | 0.88 | SYK (0.36) | USP30SYKSSTR4AAK1PDPK1 | |
| SCHEMBL25635406 | 0.84 | SYK (0.38) | USP30SYKSSTR4AAK1PDPK1 | |
| SCHEMBL16418569 | 0.81 | SYK (0.38) | USP30SYKSSTR4AAK1PDPK1 | |
| SCHEMBL31508057 | 0.81 | SYK (0.38) | USP30SYKSSTR4AAK1PDPK1 | |
| SCHEMBL30990299 | 0.81 | SSTR4 (0.39) | USP30SYKSSTR4AAK1PDPK1 | |
| SCHEMBL3434625 | 0.80 | SYK (0.35) | USP30SYKSSTR4AAK1PDPK1 | |
| SCHEMBL29513867 | 0.80 | MTNR1A (0.39) | USP30SYKSSTR4AAK1PDPK1 | |
| SCHEMBL25345974 | 0.80 | MTNR1A (0.39) | USP30SYKSSTR4AAK1PDPK1 | |
| SCHEMBL16638904 | 0.79 | SYK (0.36) | USP30SYKSSTR4AAK1PDPK1 | |
| SCHEMBL6058650 | 0.79 | SYK (0.37) | USP30SYKSSTR4AAK1PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021227906-A1 | PYRIDINE ACETAMIDE DERIVATIVE SERVING AS CDK INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州阿尔脉生物科技有限公司 | 2021-11-18 | — | — | WO | disclosed |