Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6059048 | 0.88 | SYK (0.37) | SYKUSP30AAK1PDPK1SSTR4 | |
| SCHEMBL1180650 | 0.82 | SYK (0.36) | SYKUSP30AAK1PDPK1SSTR4 | |
| SCHEMBL6058738 | 0.81 | PDPK1 (0.35) | SYKUSP30PDPK1 | |
| SCHEMBL6059494 | 0.80 | SYK (0.39) | SYKUSP30PDPK1 | |
| SCHEMBL24030998 | 0.79 | USP30 (0.37) | SYKUSP30AAK1PDPK1SSTR4 | |
| SCHEMBL16638904 | 0.79 | SYK (0.36) | SYKUSP30AAK1PDPK1SSTR4 | |
| SCHEMBL6059074 | 0.78 | SYK (0.38) | SYK | |
| SCHEMBL6058663 | 0.78 | SYK (0.38) | SYKUSP30PDPK1 | |
| SCHEMBL16690795 | 0.77 | PDPK1 (0.33) | SYKUSP30PDPK1SSTR4 | |
| SCHEMBL6059497 | 0.77 | SYK (0.34) | SYKUSP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7071175-B1 | Pyridine mercapto carboxylic acids as carboxypeptidase U inhibitors | ASTRAZENECA AB (SE) | 2006-07-04 | — | — | US | disclosed |