Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.32 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.32 |
| ▸ | NT5E | P21589 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20051999 | 0.94 | POLB (0.43) | POLBHSD17B10ABL1RIN1MAPT | |
| SCHEMBL13443489 | 0.86 | POLB (0.48) | POLBHSD17B10ABL1RIN1MAPT | |
| SCHEMBL14867643 | 0.85 | MAPT (0.41) | HSD17B10ABL1MAPTTSHRHTT | |
| SCHEMBL14867649 | 0.83 | POLB (0.31) | POLBHSD17B10 | |
| SCHEMBL20052002 | 0.78 | POLB (0.32) | POLBHSD17B10MAPTADRB2ADRB1 | |
| SCHEMBL20052001 | 0.78 | MAPT (0.44) | HSD17B10ABL1MAPTTSHRHTT | |
| SCHEMBL14867637 | 0.77 | POLB (0.68) | POLBHSD17B10ALDH1A1ADRB2ADRB1 | |
| SCHEMBL16639110 | 0.71 | POLB (0.45) | POLBABL1RIN1MAPTALDH1A1 | |
| SCHEMBL14867659 | 0.70 | KDM4E (0.39) | POLBHSD17B10TSHRL3MBTL1 | |
| SCHEMBL13896531 | 0.70 | CCNB2 (0.37) | POLBHSD17B10HTTL3MBTL1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130096289-A1 | HYDROXYMETHYL SUBSTITUTED RNA OLIGONUCLEOTIDES AND RNA COMPLEXES | MARINA BIOTECH, INC. (US) | 2013-04-18 | — | — | US | disclosed |